Results 61 to 70 of about 360,152 (355)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

The 3-dimensional anatomy of the North-Western Marsupial Mole (Notoryctes caurinus Thomas 1920) using computed tomography, X-ray and magnetic resonance imaging [PDF]

, 2003
The 3-D skeletal images obtained from reconstruction of CT scans and X-rays, and soft-tissue images produced by MRI, provide invaluable information of the internal and gross anatomy of the north-western marsupial mole (Notoryetes caurinus).
Christopher Lloyd, Swithin Song, Warburton, N., Natalie Warburton, Withers, P., Lloyd, C., Song, S., Warburton, Natalie, Wood, C., Lloyd, Christopher, Philip Withers, Wood, Christopher, Song, Swithin, Christopher Wood, Withers, Philip   +14 more
core   +1 more source

Out of Time, Out of Space, Out of Species: Deictic Displacement of the Exiled Self in Hans Sahl’s “Der Maulwurf” (The Mole)

Humanities, 2018
In Hans Sahl’s poem “Der Maulwurf” (The Mole), only the title gives an indication about the speaker’s species affiliation. The speaker of the poem suggests that he was transformed from a human into an animal.
Carla Swiderski
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

RNA Sequencing Reveals Differential Expression of Mitochondrial and Oxidation Reduction Genes in the Long-Lived Naked Mole-Rat When Compared to Mice [PDF]

, 2011
PubMed ID: 22073188This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Szafranski, K, Chris G Faulkes, Yu, Chuanfei, Coen Clive W., Faulkes Chris G., João Pedro de Magalhães, Holmes, Andrew, Platzer, M, Chuanfei Yu, Andrew Holmes, de Magalhaes, JP, Yu, C, Coen, Clive W; id_orcid, Church, GM, Szafranski, Karol, Yu Chuanfei, Platzer, Matthias, de Magalhães João Pedro, Faulkes, Chris G, Church, George M, Faulkes, CG, Holmes Andrew, Coen, CW, Matthias Platzer, George M Church, de Magalhães, João Pedro, Clive W. Coen, George M. Church, Szafranski Karol, Karol Szafranski, Holmes, A, Yang Li, Clive W Coen, Chris G. Faulkes, Li, Y, Buffenstein, R, Li Yang, Li, Yang, Buffenstein, Rochelle, Buffenstein Rochelle, Church George M., Rochelle Buffenstein, Platzer Matthias, Church, George, Faulkes, Chris G., Coen, Clive W.   +45 more
core   +1 more source

Hydatidiform mole

Journal of Osteopathic Medicine, 1997
Abstract Hydatidifonn mole is a gestational trophoblastic disease that arises from fetal rather than maternal tissue and can become metastatic. Most signs and symptoms occur late in the first trimester and are often confused with symptoms of a nonnal pregnancy and, thus, are often disregarded.
J L, Hubbard, S B, Hosmer
openaire   +2 more sources

Effects of dietary inclusion of Moringa oleifera methanolic extract on productive performance, humoral immunity and nutrient digestibility in Japanese quails

Journal of Applied Animal Research, 2023
A total of 180 unsexed, 1-day-old quail chicks were divided into four treatments (three replicates). The treatment groups were designated as MOLE-0, MOLE-1, MOLE-2 and MOLE-3. In the MOLE-0 group, quails received a basal diet without supplementation. For
Maria Imtiaz, Naila Chand, Shabana Naz, Ibrahim A. Alhidary, Sina Gul, Rifat Ullah Khan   +5 more
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Hydrological modeling of Mačkov graben using Flo-2D and HEC-HMS [PDF]

, 2016
Diplomska naloga obravnava padavinsko prispevno območje Mačkovega grabna, ki leži v severozahodnem delu porečja Gradaščice in je eno od eksperimentalnih porečij Katedre za splošno hidrotehniko UL FGG.
Mole, Marko
core  

High molecular weight hyaluronan mediates the cancer resistance of the naked mole-rat

Nature, 2013
The naked mole rat (Heterocephalus glaber) displays exceptional longevity, with a maximum lifespan exceeding 30 years. This is the longest reported lifespan for a rodent species and is especially striking considering the small body mass of the naked mole
Xiao Tian, J. Azpurua, Christopher M. Hine, Amita Vaidya, Max Myakishev-Rempel, J. Ablaeva, Z. Mao, E. Nevo, V. Gorbunova, A. Seluanov   +9 more
semanticscholar   +1 more source