Results 161 to 170 of about 7,995,512 (394)

Computational Molecular Biology

, 1996
Computational Biology is a fairly new subject that arose in response to the computational problems posed by the analysis and the processing of biomolecular sequence and structure data.
Lenhof, H., Mutzel, P., Vingron, M.
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Overexpression of Let-7a mitigates diploidization in mouse androgenetic haploid embryonic stem cells

iScience
Summary: Mouse androgenetic haploid embryonic stem cells (mAG-haESCs) can be utilized to uncover gene functions, especially those of genes with recessive effects, and to produce semicloned mice when injected into mature oocytes.
Wenteng He, Hongming Tang, Yuanyuan Li, Mingzhu Wang, Yuanyuan Li, Jiayu Chen, Shaorong Gao, Zhiming Han   +7 more
doaj   +1 more source

Additional file 2 of Systems biology approach reveals a common molecular basis for COVID-19 and non-alcoholic fatty liver disease (NAFLD)

, 2022
Shitao Jiang, Yao-Ge Liu, Lei Zhang, Xinting Sang, Yiyao Xu, Xin Lu   +5 more
openalex   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Evaluation of a web‐based resource to support a molecular biology practical class—does computer‐aided learning really work? [PDF]

, 2003
Sue Gibbins, Michael Sosabowski, Jim Cunningham   +2 more
openalex   +1 more source

Molecular biology of the mouse Q region [PDF]

, 1987
A. Eastman O'Neill, A. Winoto, A.-M. Lew, A.L. Mellor, A.L. Mellor, A.L. Mellor, C. Jaulin, C.G. Miyada, D. Cosman, D. Cosman, D. Stephan, D.A. Fisher, D.H. Schulze, D.S. Straus, E.H. Weiss, E.H. Weiss, E.H. Weiss, Elisabeth H. Weiss, F. Bregegere, I. Stroynowski, J. Geliebter, J. Klein, J. Michaelson, J. Stroynowski, J.H. Rogers, J.H. Rogers, J.J. Devlin, J.J. Devlin, J.L. Lalanne, J.L. Lalanne, L. Flaherty, L. Flaherty, L.R. Pease, M. Kress, M. Steinmetz, M. Steinmetz, R.A. Flavell, R.A. Flavell, R.S. Goodenow, S.G. Nathenson, W.L. Maloy, Y. Obata   +41 more
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

BioMoleculesAlive.org: The biochemistry and molecular biology digital library update [PDF]

, 2003
P. Craig
openalex   +1 more source

Standards for the Ph.D. Degree in the Molecular Biosciences [PDF]

, 2000
The International Union of Biochemistry and Molecular Biology, Committee on Education,
core   +1 more source