Results 161 to 170 of about 7,530,679 (394)
A long intergenic non-coding RNA regulates nuclear localization of DNA methyl transferase-1
iScience, 2021 Summary: DNA methyl transferase-1 or DNMT1 maintains DNA methylation in the genome and is important for regulating gene expression in cells. Aberrant changes in DNMT1 activity and DNA methylation are commonly observed in cancers and many other diseases ...
Rhian Jones +5 more
doaj
Atomic Biology, Electrostatics, and Ionic Channels [PDF]
New Developments and Theoretical Studies of Proteins, Ed. Ron
Elber, World Scientific Publishing, Philadelphia (1996) ISBN-10:9810221967;
ISBN-13:978-9810221966, 2008 I believe an atomic biology is needed to supplement present day molecular biology, if we are to design and understand proteins, as well as define, make, and use them. Topics in the paper are molecular biology and atomic biology. Electrodiffusion in the open channel. Electrodiffusion in mixed electrolytes. Models of permeation.
arxiv
Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies
Molecular Oncology, EarlyView.Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren +16 more
wiley +1 more source
Microsatellite instability states serve as predictive biomarkers for tumors chemotherapy sensitivity
iScience, 2023 Summary: There is an urgent need for markers to predict the efficacy of different chemotherapy drugs. Herein, we examined whether microsatellite instability (MSI) status can predict tumor multidrug sensitivity and explored the underlying mechanisms.
Taojun Ye +8 more
doaj
Stochastic approximations of higher-molecular by bi-molecular reactions [PDF]
arXiv, 2018 Biochemical reactions involving three or more reactants, called higher-molecular reactions, play an important role in theoretical systems and synthetic biology. In particular, such reactions underpin a variety of important bio-dynamical phenomena, such as multi-stability/multi-modality, oscillations, bifurcations, and noise-induced effects.
arxiv
Group testing problems in experimental molecular biology
, 1995 In group testing, the task is to determine the distinguished members of a set of objects L by asking subset queries of the form ``does the subset Q of L contain a distinguished object?'' The primary biological application of group testing is for ...
Knill, Emanuel, Muthukrishnan, S.
core +2 more sources
Molecular Oncology, EarlyView.Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink +6 more
wiley +1 more source