Results 211 to 220 of about 7,995,512 (394)

Molecular biology of tissue kallikrein [PDF]

, 1988
Raymond J. MacDonald, Harry S. Margolius, Ervin G. Erdös   +2 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Ocular Melanoma: A Comprehensive Review with a Focus on Molecular Biology. [PDF]

Int J Mol Sci
Iavarone L, Franco R, Zito Marino F, D'Abbronzo G, Argenziano G, Scharf C, Nucci G, Ronchi A, Cazzato G.   +8 more
europepmc   +1 more source

Learning Upper Level Molecular Biology Using the Yeast Two-Hybrid (Y2h) System

, 2013
Brandon M Wubben, Kim Buyert, Sam De Nooy, Nick Wilson, Tony N. Jelsma, Robbin Eppinga   +5 more
openalex   +1 more source

The Molecular Biology of Coronaviruses

Advances in Virus Research, 2006
P. Masters
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Molecular Biology of RNA

, 2015
David J. Elliott, Michael Ladomery
openalex   +2 more sources

Improvement of Performance Metrics and Security of AODV Routing Protocol using Central Dogma of Molecular Biology Based DNA Cryptography

, 2020
Gambhir Singh, Rakesh Kumar Yadav
openalex   +1 more source

The molecular biology, biochemistry, and physiology of human steroidogenesis and its disorders.

Endocrine reviews, 2011
W. Miller, R. Auchus
semanticscholar   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source