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The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
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Biology and Molecular Biology of Furoviruses
1989Publisher Summary Of the eight labile rod-shaped viruses that are transmitted by plasmodiophorid fungi, soil-borne wheat mosaic virus (SBWMV) has caused concern in some wheat-growing areas of the United States since 1919 and a disease of groundnuts now attributed to peanut clump virus (PCV) has been prevalent in India for 60 years or so.
A A, Brunt, K E, Richards
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Molecular Biology of Selenoproteins
Annual Review of Nutrition, 1990Article de synthese sur la biologie moleculaire des selenoproteines. Etude du metabolisme du selenium (Se), des quatre classes de selenoproteines, de la glutathion peroxidase (GPX) Se-dependante et non dependante, de la phospholipide hydroperoxide GPX, de la GPX plasmatique, de seleno-proteines de mammiferes (rats).
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Molecular Biology of Methanogens
Annual Review of Microbiology, 1992Methanogens are a very diverse group of the Archaea (Archaebacteria). Their genomic DNAs range from 26 to 68 mol% G+C; they exhibit all known prokaryotic morphologies and inhabit anaerobic environments as varied as the human gut and deep-sea volcanic vents.
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Molecular biology of proteasomes
Molecular Biology Reports, 1995Eukaryotic proteasomes are unusually large proteins with a heterogeneous subunit composition and have been classified into two isoforms with apparently distinct sedimentation coefficients of 20S and 26S. The 20S proteasome is composed of a set of small subunits with molecular masses of 21-32 kDa.
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