Results 251 to 260 of about 3,385,693 (328)
A Critical Review of Recent Advances in Maize Stress Molecular Biology. [PDF]
Meng L, Zhang J, Clarke N.
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Carcinogenesis Modeling: From Molecular Biology to Epidemiology
Suresh H. Moolgavkar
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This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau+9 more
wiley +1 more source
Companion Diagnostics (CDx) Based on Molecular Biology Techniques. [PDF]
Kang SL, Kwon JY, Kim SM.
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A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
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Advances in African swine fever virus molecular biology and host interactions contributing to new tools for control. [PDF]
Dixon LK.
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Molecular Biology... What Molecular (systems) Biology? [PDF]
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C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald+18 more
wiley +1 more source