Results 91 to 100 of about 4,624,977 (307)
Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis
Advanced Science, EarlyView.Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang +9 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Gonadotropin‐inhibitory hormone (GnIH, also known as RFamide‐related peptide‐3, RFRP‐3) is a hypothalamic neuropeptide that regulates vertebrate reproduction via its receptor GPR147. Although GnIH is known to mediate stress‐induced reproductive suppression, its role in broader stress responses remains unclear.
Jiani Zhang +18 more
wiley +1 more source
What is Hidden Within the Cloud?
Over the past few years cloud computing has become one of the most significant technological trends. The aim of this paper is to discuss the main characteristics of cloud computing, identify the challenges concerning the security and control of ...
Gkritsi, Aikaterini
core +1 more source
A New Cloud–Cloud Collision Source N68 toward the G35 Molecular Cloud Complex
The Astrophysical JournalBubble N68 in the G35 complex shows clear cloud–cloud collision (CCC) signatures. Its semiring-like morphology harbors many significant massive star formation tracers: 6 H ii regions, 4 6.7 GHz masers, 5 Midcourse Space Experiment sources, 9 radio peaks,
En Chen, Xi Chen
doaj +1 more source
Supernova remnants in molecular clouds [PDF]
AIP Conference Proceedings, 1999 31 pages, 4 figures, revised, in press, ApJ, Feb.
openaire +2 more sources
Cloud Services Brokerage : a survey and research roadmap [PDF]
, 2015 A Cloud Services Brokerage (CSB) acts as an intermediary between cloud service providers (e.g., Amazon and Google) and cloud service end users, providing a number of value adding services. CSBs as a research topic are in there infancy.
Barker, Adam David +6 more
core +1 more source
Advanced Science, EarlyView.This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.
Xinru Xiao +7 more
wiley +1 more source
The Astrophysical Journal LettersAstronomers have used observations of the Galactic gas and dust via infrared, microwave, and radio to study molecular clouds in extreme environments such as the Galactic center.
Samantha W. Brunker +7 more
doaj +1 more source
mSphereRepetitive extragenic palindromic (REP) sequences were first discovered in the intergenic regions of Escherichia coli and later found in phylogenetically distinct bacterial species. However, their biological roles and sequence conservation remain unclear.
Oleg N. Murashko +7 more
doaj +1 more source
Star Formation in Molecular Clouds [PDF]
Symposium - International Astronomical Union, 1985 We examine how star formation occurs in the Galaxy and come to the following conclusions. (1) The distribution of newly-born stars in the Galaxy depends on the origin of giant-molecular-cloud complexes. For individual complexes, we favor the mechanism of Parker's instability behind galactic shocks.
openaire +1 more source