Results 231 to 240 of about 3,373,419 (307)

Kinetic Jeans instability in FOG framework. [PDF]

Sci Rep
Das M, Atteya A, Karmakar PK.
europepmc   +1 more source

Chemical Bond‐Orchestrated Energy Depletion to Augment Lung Cancer Chemo‐Immunotherapy

Advanced Science, EarlyView.
This study grafted dichloroacetic acid (DCA) into perylenediimide (PDI) skeleton via ionic or covalent bond to create novel metabolic agent PDIC‐AC and PDIC‐NAC, explicitly elaborated the underlying energy metabolism and therapeutic mechanism, and developed a promising strategy for energy metabolism‐targeting chemo‐immunotherapy by chemical bond ...
Xuejie Zhao, Yuting Liu, Xiao Huang, Liwen Zhao, Chunli Li, Yongwei Huang   +5 more
wiley   +1 more source

DFDD: A Cloud-Ready Tool for Distance-Guided Fully Dynamic Docking in Host-Guest Complexation. [PDF]

J Chem Inf Model
Hengphasatporn K, Duan L, Harada R, Shigeta Y.   +3 more
europepmc   +1 more source

Unveiling the Uncharted Potential of 2D Materials in Li/Na–S Batteries: A Paradigm Shift From Graphene

Advanced Science, EarlyView.
This review explores emerging 2D materials beyond graphene, including graphdiyne, phosphorene, borophene, siloxene, MBene, antimonene, and germanene for Li/Na–S batteries. It analyzes their roles as sulfur hosts, metallic anode protectors, separators, and electrolyte fillers, emphasizing polysulfide suppression, dendrite inhibition, and interfacial ...
Naveen Kumar T. R, Xuebing Zhu, Yao‐Jie Lei, Lei Zhang, Hua Kun Liu, Weihong Lai, Guoxiu Wang, Yun‐Xiao Wang   +7 more
wiley   +1 more source

Towards globally equitable bioinformatics adoption. [PDF]

PLoS Biol
Magaña P, Gopalasingam P, Fleming JR, Kovalevskiy O, Žídek A, Ebenezer TE, Laydon A, Onions R, Akurut E, Al Sium SM, Balderas-Martínez YI, Chowdhury SF, Chowdhury S, Christie S, Dabburu GR, Fofana FG, Galiwango R, Ganji M, Jjingo D, Kakembo FE, Kebirungi G, Kiyaga S, Ksouri A, Mahtha SK, Maracaja-Coutinho V, Mason J, Molina-Mora JA, Nabisubi PPN, Nji E, Othman H, Paoletta MS, Scherer NM, Senadheera B, Turjanski AG, Twesigomwe D, Walakira A, Velankar S, Brooksbank C.   +37 more
europepmc   +1 more source

EBV‐Driven ODC1 Upregulation Enhances Polyamine Anabolism to Promote Viral Replication and Cisplatin Resistance in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
EBV‑BZLF1 initiates ODC1‑driven polyamine anabolism that correlates with poor clinical prognosis in nasopharyngeal carcinoma. The ODC1–spermidine axis promotes viral replication, cell proliferation and innate immune evasion. Pharmacological inhibition of ODC1 rescues cisplatin sensitivity, establishing ODC1 as a viable therapeutic target for EBV ...
Yueshuo Li, Xudong Hu, Chenxing Yang, Na Liu, Lin Wang, Xi Cai, Min Tang, Ya Cao, Li Shang, Feng Shi   +9 more
wiley   +1 more source

Sub-wavelength scale randomly frozen microbubble during short-pulsed-ultrasound-driven microbubble cluster dynamics in microfluidic channel. [PDF]

Ultrason Sonochem
Xu Y, Luo S, Wang Y, Wang L, Fan Y, Li F.   +5 more
europepmc   +1 more source

Bioinspired Porphyrin‐Based Catalysts From Temporospatial Confined Frameworks for Ultrafast Removal of Sulfaclozine

Advanced Science, EarlyView.
We report the rational design of artificial photocatalysts with asymmetrically coordinated dual‐metal centers and a tailored microenvironment, broadly applicable strategy is established for the synthesis of multivariate zirconium‐based metal–organic frameworks, offering a platform for precisely tuning active‐site configurations to optimize ...
Yuxin Lu, Yu‐Hang Li, Zhiyi Sun, Fanke Tong, Zelin Li, Sheng Wang, Shangkun Pei, Yi Li, Xiyan Xu, Chong‐Chen Wang, Bo Wang, Xiang Li   +11 more
wiley   +1 more source

A 3D amphioxus brain atlas illuminates the blueprint of the ancestral chordate brain and highlights unique vertebrate innovations. [PDF]

Sci Adv
Lin CY, Hsu WH, Lu MJ, Chen YH, Li KL, Chen YC, Su YH, Chou SJ, Yu JK.   +8 more
europepmc   +1 more source

Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos

Advanced Science, EarlyView.
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou, Ruixi Yu, Xuan Zhou, Feng Shi, Zeyu Lin, Peng Gao, Lujia Wang, Ninghan Feng, Zhong Wu, Dawei Wang   +9 more
wiley   +1 more source