Results 291 to 300 of about 143,809 (350)

The Foundations of Multi-line Molecular Cloud Population Synthesis

Michelle C. Perry, Daniel Sheen, Jens Kauffmann   +2 more
openalex   +1 more source

Engineering Dimensional Configuration of Single‐Atom S‐Cu‐S Sites as Reversible Electron Station for Enhanced Peroxidase‐Mimicking

Advanced Science, EarlyView.
L‐cysteine triggers auto‐assembly of POD‐like 3D biomimetic S‐Cu‐S single‐atom nanozymes on MoS2 (MoCC). MoCC shows 16.3‐fold higher catalytic velocity and 17.9‐fold greater affinity than HRP, enabling efficient •OH generation via enhanced electron inversion and transfer.
Wenjie Ma, Qian He, Jiancheng Sun, Yiqing Chen, Hongfei Su, Ludan Zhang, Xiao He, Yuguang Wang, Changjian Xie, Zhiyong Zhang, Xin Zhou, Yuliang Zhao, Wenyan Yin   +12 more
wiley   +1 more source

Two Novel S‐methyltransferases Confer Dimethylsulfide Production in Actinomycetota

Advanced Science, EarlyView.
This study identifies two novel S‐adenosine‐methionine‐dependent methyltransferases, MddM1 and MddM2, in actinomycetes from the Mariana Trench. These enzymes can convert toxic hydrogen sulfide (H2S) and methanethiol (MeSH) into dimethylsulfide (DMS), serving as a cellular detoxification and oxidative stress response.
Ruihong Guo, Zihua Guo, Yi Zhou, Yunhui Zhang, Haojin Cheng, Rebecca Devine, Chuang Sun, Ronghua Liu, Yanfen Zheng, Andrew J. Gates, Jonathan D. Todd, Xiao‐Hua Zhang   +11 more
wiley   +1 more source

High-resolution phenomics dataset collected on a field-grown, EMS-mutagenized sorghum population evaluated in hot, arid conditions. [PDF]

BMC Res Notes
Demieville J, Dilkes B, Eveland AL, Pauli D.   +3 more
europepmc   +1 more source

Heat Stress Modulates WDR5‐Mediated H3K4me3 Modification to Induce Melanogenesis via Activating CX3CL1/CX3CR1 Axis

Advanced Science, EarlyView.
This study elucidates the mechanism by which heat stress regulates skin pigmentation: heat stress upregulates CX3CL1 through the MYC‐WDR5‐H3K4me3 axis, thereby activating the CX3CL1/CX3CR1‐JNK signaling pathway and ultimately promoting melanogenesis. These findings provide novel potential therapeutic targets for pigmentary skin disorders.
Yushan Zhang, Ling Jiang, Yibo Hu, Chuhan Fu, Jinhua Huang, Jing Chen, Qinghai Zeng   +6 more
wiley   +1 more source

Methanetetrol and the final frontier in ortho acids. [PDF]

Nat Commun
Marks JH, Bai X, Nikolayev AA, Gong Q, McAnally M, Wang J, Pan Y, Fortenberry RC, Mebel AM, Yang T, Kaiser RI.   +10 more
europepmc   +1 more source

Uric Acid Functions as an Endogenous Modulator of Microglial Function and Amyloid Clearance in Alzheimer's Disease

Advanced Science, EarlyView.
Higher serum UA levels are associated with reduced AD risk in epidemiological studies. UA enhances microglial phagocytic capacity primarily by restoring CD36 and TREM2 receptor recycling that is impaired by Aβ exposure. Therapeutically, UA supplementation improves cognitive function and reduces neuropathology in AD mouse model by enhancing microglial ...
De Xie, Qiuyang Zheng, Jiaming Lv, Qian Zhang, Zhiwei Cui, Shuai Huang, Wei Yu, Binyang Chen, Wanling Que, Shanpan Fu, Yuemei Xi, Jiayu Chen, Xueling Ye, Shuyi Chen, Hairong Zhao, Tetsuya Yamamoto, Hidenori Koyama, Xin Wang, Jidong Cheng   +18 more
wiley   +1 more source

Spatial Molecular Heterogeneity on Biofunctionalized Particles Quantified by Three-Dimensional Single-Molecule DNA-PAINT. [PDF]

Langmuir
Tan WS, de Jong AM, Prins MWJ.
europepmc   +1 more source

O/C Ratio‐Driven Fluorescence Enhancement in Cellulose‐Derived Carbon Quantum Dots: Mechanistic Insights into Reaction Pathways

Advanced Science, EarlyView.
Three types of CQDs are prepared from cellulose and its derivatives via hydrothermal carbonization. An increase in the atomic O/C ratio from 0.25 to 0.61 results in a nearly seven‐fold enhancement in QY. DFT calculations verify this mechanism. Further, this study elucidates the formation pathways of cellulose‐derived CQDs and proposes a fluorescence ...
Yarong Shi, Siyu Zhao, Xiheng Kang, Xinrui Chen, Xue Ou, Meng Nan Chong, Xueping Song, Zhanying Zhang   +7 more
wiley   +1 more source

PairReg: A method for enhancing the learning of molecular structure representation in equivariant graph neural networks. [PDF]

PLoS One
Ren Z, Liu Y, Zhang S.
europepmc   +1 more source