Results 31 to 40 of about 22,673 (314)
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Review of Zeeman Effect Observations of Regions of Star Formation
Frontiers in Astronomy and Space Sciences, 2019 The Zeeman effect is the only observational technique available to measure directly the strength of magnetic fields in regions of star formation. This chapter reviews the physics of the Zeeman effect and its practical use in both extended gas and in ...
Richard M. Crutcher, Athol J. Kemball
doaj +1 more source
High altitude molecular clouds [PDF]
The Astrophysical Journal, 1994 A population of molecular clouds with a significantly greater scale height than that of Giant Molecular Clouds has been identified by examining maps of the latitude distribution of the $^{12}CO(1-0)$ emission in the first quadrant of the Galaxy. These clouds are found by identifying emission more than 2.6 times the scale-height away from the galactic ...
openaire +2 more sources
Primordial molecular clouds [PDF]
Conference on 3K cosmology, 1999 12 pages, 1 figures, Invited Talk at 3K Cosmology Conference-Roma October ...
Puy, D., Signore, M.
openaire +2 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
UniverseIn this paper, we continue the study of the thermodynamics of fluid elements in isothermal turbulent self-gravitating systems, presented by molecular clouds. We build the model again on the hypothesis that, locally, the turbulent kinetic energy per fluid
Sava D. Donkov +2 more
doaj +1 more source
On the Spatial Distribution of 13CO Structures within 12CO Molecular Clouds
The Astrophysical Journal, 2023 We look into the 2851 ^12 CO molecular clouds harboring ^13 CO structures to reveal the distribution of the projected angular separations and radial velocity separations between their internal ^13 CO structures.
Lixia Yuan +10 more
doaj +1 more source
SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas +18 more
wiley +1 more source
The Correlation Between Dust and Gas Contents in Molecular Clouds
The Astronomical JournalMolecular clouds are regions of dense gas and dust in space where new stars and planets are born. There is a strong correlation between the distribution of dust and molecular gas in molecular clouds.
Rui-Zhi Li +5 more
doaj +1 more source