Results 61 to 70 of about 473,977 (260)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

DNA-Based Molecular Communications

IEEE Access, 2018
In this paper, we propose a novel DNA-based molecular communication (MC) protocol towards high capacity communication between nanomachines for the first time in the literature. In the proposed protocol, the transmitter is capable of emitting DNA strands having different lengths as information carrying molecules. The Receiver contains receptor nanopores
Bilgesu Arif Bilgin, Ergin Dinc, Özgür B. Akan   +2 more
openaire   +2 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Modeling Interference for Diffusive Molecular Communication Under Different Biological Deployment

IEEE Access
In Molecular Communication (MC) systems, with multiple transmitting Nano Nodes, interference is one of the most challenging impairments. On the other hand, MC system highly depends on the deployment scenarios such as, Rectangular Biological Deployment ...
Suman Yadav, S. Pratap Singh, Bharat Gupta   +2 more
doaj   +1 more source

Effective Geometry Monte Carlo: A Fast and Reliable Simulation Framework for Molecular Communication

IEEE Access, 2019
Angular information of messenger molecules absorbed by a receiver plays a significant role in the molecular communication literature. In this paper, we address systematic biases and random errors in the angular information stemming from finite step sizes
Fatih Dinc, Matija Medvidovic, Leander Thiele   +2 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Information Theoretic Based Comparative Analysis of Different Communication Signals in Plants

IEEE Access, 2019
This paper compares the information-theoretic aspects of different communication signals in plants. To be specific, we consider two signals responsible for the inter-cellular communication in plants: electro-chemical and mechanosensitive signals.
Hamdan Awan, Raviraj S. Adve, Nigel Wallbridge, Carrol Plummer, Andrew W. Eckford   +4 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Nano iletişim teknolojilerinin biyomedikale katkısı

Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2018
Nano teknoloji biyomedikalalanında birçok yeni çözümler vaat etmektedir. Nano ölçekte, bir nano makinedeen temel fonksiyonları yerine getirebilen bir birimdir.
Mustafa Alper Akkaş
doaj   +1 more source