Results 71 to 80 of about 4,091,521 (342)

Molecular graphics-structural and molecular graphics descriptors in a QSAR study of 17-a-acetoxyprogesterones

Journal of the Brazilian Chemical Society, 2003
Quantitative Structure-Activity Relationship study on 21 oral progestogens, 19 of which are 17-alpha-acetoxyprogesterones, was performed by using Partial Least Squares.
Kiralj Rudolf, Ferreira Márcia M. C.
doaj  

Topological analysis of tetracyanobenzene metal–organic framework

Scientific Reports
Metal–organic frameworks (MOFs) are vital in modern material science, offering unique properties for gas storage, catalysis, and drug delivery due to their highly porous and customizable structures.
Ibrahim Al-Dayel, Muhammad Faisal Nadeem, Meraj Ali Khan   +2 more
doaj   +1 more source

DELP Treatment on Vision and Retinal Microcirculation in Patients With Acute Ischemic Stroke: Report of Five Cases and Literature Review

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li, Ronghua Hong, Hua You, Feiping Xu, Qingjun Zhang, Yiwen Lin, Yuting Su, Danmei Lan, Lingjing Jin, Junhui She   +9 more
wiley   +1 more source

Quantitative structure-activity relationship model development for estimating the predicted No-effect concentration of petroleum hydrocarbon and derivatives in the ecological risk assessment

Heliyon
Quantitative structure-activity relationship (QSAR) is a cost-effective solution to directly and accurately estimating the environmental safety thresholds (ESTs) of pollutants in the ecological risk assessment due to the lack of toxicity data.
Jiajia Wei, Lei Tian, Fan Nie, Zhiguo Shao, Zhansheng Wang, Yu Xu, Mei He   +6 more
doaj   +1 more source

Characterization of recommended banana cultivars using morphological and molecular descriptors [PDF]

Crop Breeding and Applied Biotechnology, 2009
New banana varieties with superior agronomical characteristics have been developed through introductionand/or genetic breeding. In order to guarantee its marketing and intellectual property, these new varieties need to becharacterized by efficient ...
Onildo Nunes de Jesus, Cláudia Fortes Ferreira, Sebastião de Oliveira e Silva, Terezinha Rangel Câmara, Taliane Leila Soares, Kátia Nogueira Pestana   +5 more
doaj  

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Prediction of metabolism and solubility of tablet-form drugs according to the biopharmaceutical drug disposition classification system

ADMET and DMPK
Background and purpose: Prediction of metabolism and solubility of tablet-form drugs is essential in pharmaceutical development, impacting drug efficacy, safety and formulation strategies.
Yaroslava Pushkarova, Galina Zaitseva , Kaouthar Bouaalam   +2 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

QSAR study of some chalcones derivatives for prediction of anti-prostate cancer activities [PDF]

شیمی کاربردی روز, 2012
We performed structure-activity studies upon an extended series of 36 compounds of chalcone derivatives with anti cancer biological activities in LNCaP prostate cancer cell line, using QSAR methods that imply analysis of correlations and multiple linear ...
Abbas Amini Manesh, , Zahra Rostami, Maryam Frouzandeh   +2 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source