Results 51 to 60 of about 14,124,181 (261)

MOLECULAR DESIGN OF N-ACYL DERIVATIVES OF 2-(2-OXOPYROLIDIN-1-YL)-ACETAMIDE WITH GABA-ERGIC AND GLUTAMATERGIC ACTIVITIES

open access: yesФармация и фармакология (Пятигорск), 2021
The first of the most successfully implemented nootropic drugs in medical practice is piracetam, which should be attributed to cyclic derivatives of gamma-aminobutyric acid.
I. P. Kodonidi   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Design and Performance Studies on Series of Tetrazole-Based Ultra-High-Energy Density High-Nitrogen Heterocyclic Power Systems

open access: yesEnergies
The innovation of energy storage technology and its solutions for energetic materials is an important direction in the current energy technology field. Hence, series of tetrazole-based ultra-high-energy-density high-nitrogen heterocyclic power compounds ...
Yunqiu Li, Qiyao Yu
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Design for Public Good [PDF]

open access: yes, 2013
In this publication, members of SEE share experiences of enhancing design in public sector ...
Design Council, UK
core  

Tacit learning in an extended interior design studio [PDF]

open access: yes
5th DRS Learn X Design International Conference for Design Education Researchers: Insider Knowledge, 9-12 July 2019, METU, Ankara202403 bckwVersion of RecordSelf ...
Venkatesh, A, Ma, H
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Design Education as a Catalyst for Change

open access: yes, 2018
Designers play a role in shaping our world, both literally and figuratively. Human lives are spent interacting with designed artefacts, systems, and processes.
Mulder, Ingrid   +9 more
core   +1 more source

Antimicrobial Peptide Nanoassemblies: Design, Response Mechanisms, and Biomedical Applications

open access: yesMolecules
The overuse of antibiotics has accelerated the evolution and mutation of drug-resistant bacteria, creating an urgent need for novel antimicrobial drugs and feed additives.
Tao Wang   +11 more
doaj   +1 more source

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