Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Diffusion-Less Recrystallization at High Uniaxial Deformation [PDF]
Журнал нано- та електронної фізики, 2012 It was shown by computer simulation that coarsened grains with lower content of defects are formed at uniaxial deformation of a four-grain infinite nano-wire. The structure similar to crystal filaments was formed in the case of tension.
L.S. Metlov, A.V. Zavdoveev
doaj
Single-molecule FRET and molecular diffusion analysis characterize stable oligomers of amyloid-β 42 of extremely low population. [PDF]
PNAS Nexus, 2023 Meng F, Kim JY, Gopich IV, Chung HS.
europepmc +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Cell-Sized Confinements Alter Molecular Diffusion in Concentrated Polymer Solutions Due to Length-Dependent Wetting of Polymers. [PDF]
ACS Mater Au, 2023 Kanakubo Y +6 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
Molecular Diffusion and Self-Assembly: Quantifying the Influence of Substrate hcp and fcc Atomic Stacking. [PDF]
Nano Lett, 2022 Edmondson M, Saywell A.
europepmc +1 more source
FEBS Open Bio, EarlyView.Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar +11 more
wiley +1 more source
Translational diffusion coefficients and hydrodynamic radii of normal corn starch in aqueous media from asymmetrical flow field-flow fractionation experiments [PDF]
, 2011 Starch is a highly disperse material with broad distributions of molecular sizes and geometries. Its dissolution in aqueous media is difficult to achieve and it tends to form aggregates through both inter- and intra-molecular interactions.
Huber, Anton, Juna, Shazia
core +1 more source
Boosting molecular diffusion following the generalized Murray's Law by constructing hierarchical zeolites for maximized catalytic activity. [PDF]
Natl Sci Rev, 2022 Sun MH +10 more
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