Results 191 to 200 of about 8,517,557 (393)

Towards Selective Binding to the GLUT5 Transporter: Synthesis, Molecular Dynamics and In Vitro Evaluation of Novel C-3-Modified 2,5-Anhydro-D-mannitol Analogs [PDF]

, 2022
Natasha Rana, M. Abdel Aziz, Ahmed K. Oraby, Melinda Wuest, Jennifer Dufour, Khaled A. M. Abouzid, Frank Wuest, F. G. West   +7 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Gut microbiota diversity among humans, elephants, livestock and wild herbivores in Chitwan National Park bears implications for conservation medicine

Scientific Reports
Gut microbiome influences host health and well-being. Co-occurring hosts may exchange disease-causing bacteria belonging to these microbial communities.
Rajesh Man Rajbhandari, Giovanni Forcina, Prajwol Manandhar, Pragun G. Rajbhandari, Rajindra Napit, Roji Raut, Seily Shrestha, Amir Sadaula, Christian Gortázar, Paulo Célio Alves, José de la Fuente, João Queirós, Dibesh Karmacharya   +12 more
doaj   +1 more source

Redox Properties of Native and Damaged DNA from Mixed Quantum Mechanical/Molecular Mechanics Molecular Dynamics Simulations

, 2020
Polydefkis Diamantis, Ivano Tavernelli, Ursula Röthlisberger   +2 more
openalex   +2 more sources

Structure Refinement of the OpcA Adhesin Using Molecular Dynamics [PDF]

, 2007
Binquan Luan, Martin Caffrey, Aleksei Aksimentiev   +2 more
openalex   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

IGF2BP3 promotes mRNA degradation through internal m7G modification

Nature Communications
Recent studies have suggested that mRNA internal m7G and its writer protein METTL1 are closely related to cell metabolism and cancer regulation. Here, we identify that IGF2BP family proteins IGF2BP1-3 can preferentially bind internal mRNA m7G.
Chang Liu, Xiaoyang Dou, Yutao Zhao, Linda Zhang, Lisheng Zhang, Qing Dai, Jun Liu, Tong Wu, Yu Xiao, Chuan He   +9 more
doaj   +1 more source

Interplay of physically different properties leading to challenges in separating lanthanide cations – an ab initio molecular dynamics and experimental study [PDF]

, 2021
Kevin Leung, Anastasia G. Ilgen, Louise J. Criscenti, Kevin Leung, Anastasia G. Ilgen, Louise J. Criscenti   +5 more
openalex   +1 more source

A unified formulation of the constant temperature molecular dynamics methods

, 1984
S. Nosé
semanticscholar   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source