Results 211 to 220 of about 5,499,417 (372)

Integrating molecular genetics with plant breeding to deliver impact. [PDF]

Plant Physiol
Sharma R, Yang CJ, Rossi N, Irving E, Tuffin A, Aliki H, Powell W, Dawson IK.   +7 more
europepmc   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Editorial for the Special Issue "Advances in Cattle, Sheep, and Goats Molecular Genetics and Breeding". [PDF]

Genes (Basel)
Cao X.
europepmc   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Milestone Review: The History of Molecular Genetics Analysis of Alzheimer's Disease. [PDF]

J Neurochem
Hardy J.
europepmc   +1 more source

Molecular genetics of gastrointestinal non-Hodgkin‧s lymphomas: unusual prevalence and pattern of c-myc rearrangements in aggressive lymphomas [PDF]

, 1990
JH van Krieken, Mark Raffeld, S Raghoebier, ES Jaffe, GJ van Ommen, PM Kluin   +5 more
openalex   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Research Progress in Hematological Malignancies: A Molecular Genetics Perspective. [PDF]

Genes (Basel)
Kansal R.
europepmc   +1 more source

Molecular genetics of cancer. [PDF]

, 1992
B. A. J. Ponder
openalex   +1 more source

Molecular genetics and conservation in the Galápagos [PDF]

, 1996
Rassmann, Kornelia
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