Results 41 to 50 of about 631,800 (281)

Computing the blocks of a quasi-median graph [PDF]

, 2014
Quasi-median graphs are a tool commonly used by evolutionary biologists to visualise the evolution of molecular sequences. As with any graph, a quasi-median graph can contain cut vertices, that is, vertices whose removal disconnect the graph.
Ayling, Bandelt, Bandelt, Bandelt, Bandelt, Bandelt, Bandelt, Bandelt, Diestel, Dress, Dress, Dress, Felsenstein, Foulds, Huson, Imrich, Misra, Mulder, Schwarz, Sven Herrmann, Vincent Moulton   +20 more
core   +2 more sources

Molecular graph contrastive learning with line graph

Pattern Recognition
Trapped by the label scarcity in molecular property prediction and drug design, graph contrastive learning (GCL) came forward. Leading contrastive learning works show two kinds of view generators, that is, random or learnable data corruption and domain knowledge incorporation.
Xueyuan Chen, Shangzhe Li, Ruomei Liu, Bowen Shi, Jiaheng Liu, Junran Wu, Ke Xu   +6 more
openaire   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Computing First General Zagreb Index of Operations on Graphs

IEEE Access, 2019
The numerical coding of the molecular structures on the bases of topological indices plays an important role in the subject of Cheminformatics which is a combination of Computer, Chemistry, and Information Science.
Jia-Bao Liu, Saira Javed, Muhammad Javaid, Khurram Shabbir   +3 more
doaj   +1 more source

Molecular Graph Canonicalization

, 2021
Many kinds of molecular encoding are used in cheminformatics, but all are based on the concept of a molecular graph. A molecular graph is a graph whose nodes and edges are augmented to capture information relevant to molecular structure. Generally speaking, atoms map to nodes and bonds map to edges.
openaire   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Mapping Connectivity Patterns: Degree-Based Topological Indices of Corona Product Graphs

Journal of Applied Mathematics, 2023
Graph theory (GT) is a mathematical field that involves the study of graphs or diagrams that contain points and lines to represent the representation of mathematical truth in a diagrammatic format. From simple graphs, complex network architectures can be
Nasir Ali, Zaeema Kousar, Maimoona Safdar, Fikadu Tesgara Tolasa, Enoch Suleiman   +4 more
doaj   +1 more source

Variable exponent Hardy spaces associated with discrete Laplacians on graphs

, 2017
In this paper we develop the theory of variable exponent Hardy spaces associated with discrete Laplacians on infinite graphs. Our Hardy spaces are defined by square integrals, atomic and molecular decompositions.
Almeida, Víctor, Betancor, Jorge J., Castro, Alejandro J., Rodríguez-Mesa, Lourdes   +3 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Multi-view mixture-of-experts for predicting molecular properties using SMILES, SELFIES, and graph-based representations

Machine Learning: Science and Technology
Chemical foundation models are generally based on a two-step approach-pre-training on unlabeled data followed by fine-tuning on specific tasks-to boost model capacity.
Eduardo Soares, Victor Yukio Shirasuna, Emilio Vital Brazil, Indra Priyadarsini, Seiji Takeda   +4 more
doaj   +1 more source