Results 71 to 80 of about 631,800 (281)
Random Network Behaviour of Protein Structures
, 2009 Geometric and structural constraints greatly restrict the selection of folds adapted by protein backbones, and yet, folded proteins show an astounding diversity in functionality.
V., Brinda K. +2 more
core +1 more source
, 2014 Citation: 'molecular graph' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.MT07069 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Predicting Graph Categories from Structural Properties [PDF]
, 2018 Complex networks are often categorized according to the underlying phenomena that they represent such as molecular interactions, re-tweets, and brain activity.
Ahmed, Nesreen K +7 more
core +2 more sources
Encoding and Selecting Coarse-Grain Mapping Operators with Hierarchical Graphs
, 2018 Coarse grain (CG) molecular dynamics (MD) can simulate systems inaccessible to fine grain (FG) MD simulations. A CG simulation decreases the degrees of freedom by mapping atoms from an FG representation into agglomerate CG particles. The FG to CG mapping
Chakraborty, Maghesree +2 more
core +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Computing F-index, coindex and Zagreb polynomials of the kth generalized transformation graphs
Heliyon, 2020 In chemical graph theory, forgotten topological index or F-index plays a crucial role to collect information about the properties of chemical compounds. The kth generalized transformation graphs of a molecular graph preserve the entire information on the
Durbar Maji, Ganesh Ghorai
doaj +1 more source
Molecular graph generation with Graph Neural Networks
, 2020 20 pages, 4 figures (2 figures are composed of double images, for a total of 6 images)
Bongini, Pietro +2 more
openaire +2 more sources
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Multiresolution equivariant graph variational autoencoder
Machine Learning: Science and Technology, 2023 In this paper, we propose Multiresolution Equivariant Graph Variational Autoencoders (MGVAE), the first hierarchical generative model to learn and generate graphs in a multiresolution and equivariant manner. At each resolution level, MGVAE employs higher
Truong Son Hy, Risi Kondor
doaj +1 more source