Results 121 to 130 of about 1,120,591 (303)

Characterization of high-quality MgB2(0001) epitaxial films on Mg(0001)

, 2005
High-grade MgB2(0001) films were grown on Mg(0001) by means of ultra-high-vacuum molecular beam epitaxy. Low energy electron diffraction and x-ray diffraction data indicate that thick films are formed by epitaxially oriented grains with MgB2 bulk ...
, Andrea Goldoni, Antropov V P, Cinzia Cepek, Golubov A A, Hellsing B, Lee S, Luca Petaccia, Macovez R, Massimo Sancrotti, Mattevi C, Roberto Macovez, Rosanna Larciprete, Silvano Lizzit   +13 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Molecular Mapping of Putative Genomic Regions Controlling Fruit and Seed Morphology of Watermelon. [PDF]

Int J Mol Sci, 2023
Yang T, Amanullah S, Li S, Cheng R, Zhang C, Zhao Z, Liu H, Luan F, Wang X.   +8 more
europepmc   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Molecular mapping of a core transcriptional signature of microglia-specific genes in schizophrenia. [PDF]

Transl Psychiatry, 2023
Fiorito AM, Fakra E, Sescousse G, Ibrahim EC, Rey R.   +4 more
europepmc   +1 more source

LYNDS 379 - a new source of bipolar molecular flow [PDF]

, 1986
A study has been made incorporating molecular line CO J = 2-1 and optical star counting techniques of the sharp-edged Lynds dark cloud 379. It is found to lie at a distance of 200 pc, and to have an average extinction, AB, of
Cronin, Nigel J., Hilton, John, Rainey, Ruth, White, Glenn J.   +3 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Molecular mapping of two novel cold resistance genes in common wheat by 660K SNP array. [PDF]

Mol Breed, 2023
Lei C, Li M, Chen Z, He W, Liu B, Liu S, Li X, Xie Y.   +7 more
europepmc   +1 more source