Results 121 to 130 of about 1,325,148 (262)

DCDC2C Protein Expression in Human Spermatozoa: A Potential Molecular Marker for Asthenozoospermia. [PDF]

Med Sci (Basel)
Adli O, Rachid E, Kbirou A, Rochdi C, Filali M, Louanjli N, Assou S, Aboutaieb R.   +7 more
europepmc   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Punctual mutations in lipoxygenase sequence expressed in black soybean seed coat

Journal of Seed Science
Lipoxygenase enzymes are relevant in several characteristics of soybean seeds, such as germination performance, storage capacity and tolerance to infection by microorganisms.
Liliane Marcia Mertz, Fernando Augusto Henning, Ana Paula Piccinin Barbieri, Samantha Rigo Segalin, Francisco Carlos Krzyzanowski, Paulo Dejalma Zimmer   +5 more
doaj  

Rapid Assessment of Carotenoid and Gluten Quality Traits in Durum Wheat Hybrids Confirmed by Biochemical and Molecular Marker Analyses. [PDF]

Life (Basel)
Utebayev M, Dashkevich S, Kradetskaya O, Chilimova I, Zhylkybaev R, Zhigula T, Shelayeva T, Khassanova G, Kuzbakova M, Sharipova B, Shavrukov Y.   +10 more
europepmc   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Integrative transcriptomic and experimental analyses prioritize TPT1 as a PANoptosis-associated candidate molecular marker in sarcopenia. [PDF]

Front Cell Dev Biol
Dong S, Wang M, Liang C, Xu P, Ye Z, Yao J, Tang Z, Ou T, Zhao X, Dai X, Li Y, Ji G.   +11 more
europepmc   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Molecular marker of memory formation reveals complex mechanisms of developmental learning. [PDF]

BMC Neurosci
Butler RM, Delis KD, Maheshwar KV, Montañez KD, Yalcindag S, London SE.   +5 more
europepmc   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Evaluation of promising interspecific tomato rootstocks (Solanum lycopersicum × Solanum habrochaites) for molecular marker-based resistance screening, yield, and fruit quality. [PDF]

BMC Plant Biol
Yücel HŞ, Seçim A.
europepmc   +1 more source