Results 121 to 130 of about 2,014,208 (347)

Molecular marker genotypes, heterozygosity and genetic interactions explain heterosis in Arabidopsis thaliana [PDF]

, 2004
Naeem H. Syed, Zi‐Jiang Chen
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Principal molecular markers

, 2021
Molecular markers are molecular phenotypes originating from any expressed or unexpressed segments of DNA that come from genetic inheritance and lend themselves to the differentiation of one or more individuals. It can be classified into two groups: the first, markers are obtained by hybridization and the second, markers are obtained by DNA ...
Oliveira, Altacis Junior, Oliveira, Taniele Carvalho de, Santos, Andressa Alves Cabreira dos, Siqueira, Thalyson Ade, Duarte, Willian Martins, Caldeira, Daniela Soares Alves, Vilarinho, Marcella Karoline Cardoso, Almici, Mirian da Silva, Silva, Gustavo Ferreira da, Barelli, Marco Antonio Aparecido, Karsburg, Isane Vera   +10 more
openaire   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Definition of progression risk based on combinations of cellular and molecular markers in patients with Binet stage A chronic lymphocytic leukaemia [PDF]

, 2009
Fortunato Morabito, Giovanna Cutrona, Massimo Gentile, Serena Matis, Katia Todoerti, Monica Colombo, C. Sonaglio, Sonia Fabris, Daniele Reverberi, Mauro Megna, Mauro Spriano, Eugenio Lucia, Edoardo Rossi, Vincenzo Callea, Carla Mazzone, Gianluca Festini, Simona Zupo, Stefano Molica, Antonino Neri, Manlio Ferrarini   +19 more
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Molecular marker v1

, 2019
SSR and SRAP markers were employed to assess the genetic diversity and structure of sixty-four samples from four populations ofEmmenopterys henryi. Twelve pairs of SRAP primers generated 86 bands, and polymorphism rate was 88.37%. 148 polymorphic alleles were detected by ten pairs of SSR primers, with an average number of polymorphic alleles per primer
Yanli Niu, Yansong Peng, Wenxing Chen, Wenxing Chen, Sadaruddin Chachar, Pingxian Zhang, Saixia Zhou, Yuan Gao   +7 more
openaire   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Molecular markers of human sperm functions [PDF]

, 2008
Monica Muratori, Michaela Luconi, Sara Marchiani, Gianni Forti, Elisabetta Baldi   +4 more
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Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Proceedings of the COST SUSVAR/ECO-PB Workshop on organic plant breeding strategies and the use of molecular markers [PDF]

, 2005
In many countries,national projects are in progress to investigate the sustainable low-input approach.In the present COST network,these projects are coordinated by means of exchange of materials,establishing common methods for assessment and statistical ...

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