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HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

The emerging role of cell-free DNA as a molecular marker for duodenal adenocarcinoma. [PDF]

open access: yesJ Chin Med Assoc
Lai HF   +5 more
europepmc   +1 more source

Efficient arabinoxylan assay for wheat: Exploring variability and molecular marker associations in Wholemeal and refined flour. [PDF]

open access: yesJ Cereal Sci
Hernández-Espinosa N   +5 more
europepmc   +1 more source

Table S1 from Comprehensive Multiomics Characterization of Perineural Invasion in Cervical Cancer Reveals Diagnostic Markers, Molecular Drivers, and Therapeutic Strategies

open access: gold
Ting Wan   +12 more
openalex   +1 more source
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Molecular Markers

2023
Conventionally, establishment of relationship between the genotype and phenotype through genetic analysis was considered as key to success in plant breeding. The discovery of molecular markers has changed the entire scenario of genome analysis. Coinheritance of a gene of interest and a marker suggests that they are physically close on the chromosome ...
C. Judith Betsy, C. Siva
openaire   +2 more sources

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