Results 161 to 170 of about 7,421,514 (390)

Molecular markers in maize breeding [PDF]

open access: yesSelekcija i Semenarstvo, 2011
Today the marker assisted selection (MAS) is being routinely applied in breeding programs of large private companies. However, the implementation of molecular markers for commercial use in small companies and public sec- tor is on a considerably smaller ...
Treskić Sanja   +7 more
doaj  

Integration of microsatellite (SSR) markers in Hevea spp. reference genetic map : a powerful tool for genetic analysis of qualitative and quantitative agronomic traits [PDF]

open access: yes, 2008
In 2000, was published (Lespinasse et al. 2000) the 1st genetic map of rubber tree (Hevea spp.). This saturated map encompassed 717 loci, allowing an efficient coverage of the 18 chromosomes of the Hevea genome, and it can be considered as the reference ...
Fouet, Olivier   +3 more
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Is telomere length a molecular marker of past thermal stress in wild fish? [PDF]

open access: hybrid, 2016
Paul V. Debes   +4 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

ISSR markers as a tool to differentiate genotypes of Cinchona hybrids propagated in vitro and ex vitro

open access: yesRevista Colombiana de Biotecnología
The differentiation of Cinchona spp. hybrids genotypes are challenging due to their shared origins and morphological similarities. This study utilized ISSR (Inter Simple Sequence Repeat) markers to distinguish between genotypes of Cinchona spp.: LF40 ...
Juan David Saavedra Correa   +2 more
doaj   +1 more source

A Genetic Linkage Map Using an F1 Population in Rubber Tree (Hevea brasiliensis) based on microsatellite markers. P0527 [PDF]

open access: yes, 2012
The construction of molecular gene linkage map in Hevea requires specific methodology because of high heterozygosity. Unlike annual crops, a cross between two heterozygous parents in Hevea can yield information up to four alleles, which are segregated ...
Garcia, Antonio Augusto Franco   +7 more
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

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