Results 31 to 40 of about 33,280,657 (326)
Visualizing group II intron dynamics between the first and second steps of splicing
Nature Communications, 2020 Group II introns are self-splicing ribozymes. Here, the authors employ enzymatic assay, X-ray crystallography and molecular dynamics simulations to show that protonation of the group II intron catalytic triad plays an important role for the transition ...
Jacopo Manigrasso +7 more
doaj +1 more source
EAG Responses Increase of Antennae after a Single Pheromone Pulse
Natural Product Communications, 2014 Increased behavioral sensitivity to the pheromone after brief exposure of the whole insect to the sex pheromone has been documented in antennal lobe neurons of Spodoptera littoralis . We investigated whether a brief stimulus of the major component of the
Carmen Quero +2 more
doaj +1 more source
Frontiers in Physiology, 2020 Signaling pathways involve complex molecular interactions and are controled by non-linear regulatory mechanisms. If details of regulatory mechanisms are not fully elucidated, they can be implemented by different, equally reasonable mathematical ...
Janina Mothes +5 more
doaj +1 more source
Molecular Simulation, 2019 Metal-organic frameworks (MOFs) are highly tuneable, extended-network, crystalline, nanoporous materials with applications in gas storage, separations, and sensing.
Arni Sturluson +12 more
semanticscholar +1 more source
3D QSAR of Pyrrolo Pyrimidine and Thieno Pyrimidines as Human Thymidylate Synthase Inhibitors
E-Journal of Chemistry, 2012 Thymidylate synthase (TS) is a crucial enzyme for DNA biosynthesis and many nonclassical lipophilic antifolates targeting this enzyme are quite efficient and encouraging as antitumor drugs.
K. Meena Kumari +2 more
doaj +1 more source
Influence of Magnetic Field on Atrazine Adsorption and Degradation by Ferroxite and Hematite
MagnetismThis study approaches the characterization of Ferroxite and Hematite and the test of their magnetic properties on the degradation and adsorption of Atrazine, an herbicide of the triazine class.
Marcos Antônio Sousa +6 more
doaj +1 more source
Controlling Nuclear NF-κB Dynamics by β-TrCP—Insights from a Computational Model
Biomedicines, 2019 The canonical nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway regulates central processes in mammalian cells and plays a fundamental role in the regulation of inflammation and immunity. Aberrant regulation of
Uwe Benary, Jana Wolf
doaj +1 more source
Journal of Chemical Theory and Computation, 2015 Nanodiscs are discoloidal protein-lipid particles that self-assemble from a mixture of lipids and membrane scaffold proteins. They form a highly soluble membrane mimetic that closely resembles a native-like lipid environment, unlike micelles. Nanodiscs are widely used for experimental studies of membrane proteins.
Iwona, Siuda, D Peter, Tieleman
openaire +2 more sources
Molecular Modelling of the Complex Polysaccharide Heparan Sulphate [PDF]
Heparan Sulphate plays an important role in many life processes and so an understanding of its role as a universal co-receptor is of great importance. Traditionally oligosaccharides derived from the related molecule heparin have been at the forefront of
Swift, Simone
core +3 more sources
Multiscale Molecular Modelling of ATP-fueled Supramolecular Polymerisation and Depolymerisation [PDF]
, 2020 Fuel-regulated self-assembly is a key principle by which Nature creates spatiotemporally controlled materials and dynamic molecular systems that are in continuous communication (molecular exchange) with the external environment.
Giovanni M., Pavan +4 more
core +1 more source