Results 191 to 200 of about 2,051,496 (327)

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Machine learning- and multilayer molecular network-assisted screening hunts fentanyl compounds. [PDF]

Sci Adv
Shi C, Li W, Wang Y, Chen X, Yu M, Zhang H, You Z, Song M, Deng X, Fang M.   +9 more
europepmc   +1 more source

Extended Master Equation Models for Molecular Communication Networks [PDF]

, 2013
Chun Tung Chou
openalex   +1 more source

Mechanical Behavior of Hybrids with Hyper-Connected Molecular Networks

, 2021
Reinhold H. Dauskardt
openalex   +2 more sources

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

Molecular network of metabolic reprogramming and precision diagnosis and treatment of hepatocellular carcinoma. [PDF]

Biomark Res
An L, Li Z.
europepmc   +1 more source

A detailed molecular network map and model of the NLRP3 inflammasome. [PDF]

Front Immunol, 2023
Krantz M, Eklund D, Särndahl E, Hedbrant A.   +3 more
europepmc   +1 more source

The Molecular Comorbidity Network of Periodontal Disease [PDF]

Mireya Martínez-García, Enrique Hernández–Lemus   +1 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Integrating machine learning and molecular dynamics simulation to decipher the molecular network of dioxin-associated liposarcoma. [PDF]

Sci Rep
Chenhe Z, Aobo Z, Xiao Z, Han G, Longshang W, Zhe X, Yingxue C, Huichen L, Jincheng W, Wei Z, Wengang L.   +10 more
europepmc   +1 more source