ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel +8 more
wiley +1 more source
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
Diversity of Molecular-Network Conformations in the Over-Stoichiometric Arsenoselenides Covering a Full <i>Thioarsenides</i> Row As<sub>4</sub>Se<sub>n</sub> (0 ≤ <i>n</i> ≤ 6). [PDF]
Shpotyuk O +4 more
europepmc +1 more source
Objective Recent inflammatory bowel disease (IBD) treatment guidelines have recommended against nonsteroidal anti‐inflammatory drug (NSAID) use despite prevalent musculoskeletal symptoms and opioid overuse in this population. Given the discordance between changing national guidelines and potential clinical utility, we sought to assess national temporal
Adam S. Mayer +5 more
wiley +1 more source
Drug Repurposing Using Molecular Network Analysis Identifies Jak as Targetable Driver in Necrobiosis Lipoidica. [PDF]
Hughes AN +10 more
europepmc +1 more source
Insights into the molecular network characteristics of major HIV-1 subtypes in developed Eastern China: a study based on comprehensive molecular surveillance data. [PDF]
Fan Q +16 more
europepmc +1 more source
Identifying distinct markers in two Sorghum varieties for baijiu fermentation using untargeted metabolomics and molecular network approaches. [PDF]
Li Y +6 more
europepmc +1 more source
Molecular network mechanism in cerebral ischemia-reperfusion rats treated with human urine stem cells. [PDF]
Zhang LC +9 more
europepmc +1 more source

