Results 31 to 40 of about 380,132 (123)
Aging cellular networks: chaperones as major participants
, 2006 We increasingly rely on the network approach to understand the complexity of cellular functions. Chaperones (heat shock proteins) are key "networkers", which have among their functions to sequester and repair damaged protein. In order to link the network
Agoston +56 more
core +1 more source
Discovery methods for systematic analysis of causal molecular networks in modern omics datasets [PDF]
arXiv, 2022 With the increasing availability and size of multi-omics datasets, investigating the casual relationships between molecular phenotypes has become an important aspect of exploring underlying biology and genetics. This paper aims to introduce and review the available methods for building large-scale causal molecular networks that have been developed in ...
arxiv
Optimizing information flow in small genetic networks. I
, 2009 In order to survive, reproduce and (in multicellular organisms) differentiate, cells must control the concentrations of the myriad different proteins that are encoded in the genome. The precision of this control is limited by the inevitable randomness of
A. Arkin +14 more
core +1 more source
Florigens and antiflorigens: a molecular genetic understanding [PDF]
Essays In Biochemistry 58, 133-149. Portland Press (2015), 2015 Florigens, the leaf-derived signals that initiate flowering, have been described as mysterious, elusive and the Holy Grail of plant biology.
arxiv +1 more source
Glioma targeted therapy: insight into future of molecular approaches
Molecular Cancer, 2022 Gliomas are the common type of brain tumors originating from glial cells. Epidemiologically, gliomas occur among all ages, more often seen in adults, which males are more susceptible than females.
Keyang Yang +13 more
semanticscholar +1 more source
Modeling Evolution of Crosstalk in Noisy Signal Transduction Networks
, 2017 Signal transduction networks can form highly interconnected systems within cells due to network crosstalk, the sharing of input signals between multiple downstream responses.
Mukhopadhyay, Ranjan +2 more
core +1 more source
Molecules, 2022 Raw Ephedrae herba (REH) and honey-processed Ephedrae herba (HEH) were the different decoction pieces of Ephedrae herba (EH). Honey-processing that changes REH into HEH has been shown to relieve cough and asthma to a synergistic extent.
Hengyang Li +10 more
semanticscholar +1 more source
Assessing the significance of knockout cascades in metabolic networks
, 2012 Complex networks have been shown to be robust against random structural perturbations, but vulnerable against targeted attacks. Robustness analysis usually simulates the removal of individual or sets of nodes, followed by the assessment of the inflicted ...
Basler, Georg +4 more
core +1 more source
Numerical Investigation of Graph Spectra and Information Interpretability of Eigenvalues
, 2015 We undertake an extensive numerical investigation of the graph spectra of thousands regular graphs, a set of random Erd\"os-R\'enyi graphs, the two most popular types of complex networks and an evolving genetic network by using novel conceptual and ...
A.N. Kolmogorov +7 more
core +1 more source
Causal Discovery for Gene Regulatory Network Prediction [PDF]
arXiv, 2023 Biological systems and processes are networks of complex nonlinear regulatory interactions between nucleic acids, proteins, and metabolites. A natural way in which to represent these interaction networks is through the use of a graph. In this formulation, each node represents a nucleic acid, protein, or metabolite and edges represent intermolecular ...
arxiv