Results 41 to 50 of about 380,132 (123)

Using transcriptomic and metabolomic data to investigate the molecular mechanisms that determine protein and oil contents during seed development in soybean

Frontiers in Plant Science, 2022
Soybean [Glycine max (L.) Merri.] is one of the most valuable global crops. And vegetable soybean, as a special type of soybean, provides rich nutrition in people’s life.
Wenjing Xu, Qiong Wang, Wei Zhang, Hongmei Zhang, Xiaoqing Liu, Q. Song, Yuelin Zhu, Xiaoyan Cui, Xin Chen, Huatao Chen   +9 more
semanticscholar   +1 more source

Dynamics of gene expression and the regulatory inference problem

, 2008
From the response to external stimuli to cell division and death, the dynamics of living cells is based on the expression of specific genes at specific times.
, Alon U., Chen W. England J. Shakhnovich E., Hertz J., Honerkamp J., J. Berg, Lèbre S., Michaelis L., Spellman P. T., Stokic D. Hanel R. Thurner S., van Kampen N.   +10 more
core   +1 more source

Bond Graphs Unify Stoichiometric Analysis and Thermodynamics [PDF]

arXiv, 2020
Whole-cell modelling is constrained by the laws of nature in general and the laws of thermodynamics in particular. This paper shows how one prolific source of information, stoichiometric models of biomolecular systems, can be integrated with thermodynamic principles using the bond graph approach to network thermodynamics.
arxiv  

Any Stochastic Reaction Network has a Stationary Measure [PDF]

arXiv, 2023
In this note, we use a result by Harris (1957) to show that there always exists a stationary measure (not necessarily a distribution) on a closed irreducible component of a stochastic reaction network. This measure might not be unique. In particular, any weakly reversible stochastic reaction network has a stationary measure on all closed irreducibe ...
arxiv  

Action Mechanism Underlying Improvement Effect of Fuzi Lizhong Decoction on Nonalcoholic Fatty Liver Disease: A Study Based on Network Pharmacology and Molecular Docking

Evidence-Based Complementary and Alternative Medicine, 2022
Objective This study aimed to decipher the bioactive compounds and potential mechanism of traditional Chinese medicine (TCM) formula Fuzi Lizhong Decoction (FLD) for nonalcoholic fatty liver disease (NAFLD) treatment via an integrative network ...
Zheng Luo, luyun xia, Yuqin Tang, Lili Huang, Dan Liu, Wenhui Huai, Chunjiang Zhang, Yan-qiu Wang, Yong-Mei Xie, Q. Yin, Yunhui Chen, Tian E. Zhang   +11 more
semanticscholar   +1 more source

Multistability of Small Reaction Networks [PDF]

arXiv, 2020
For three typical sets of small reaction networks (networks with two reactions, one irreversible and one reversible reaction, or two reversible-reaction pairs), we completely answer the challenging question: what is the smallest subset of all multistable networks such that any multistable network outside of the subset contains either more species or ...
arxiv  

Physiological and molecular mechanisms of the response of roots of Pinus massoniana Lamb. to low-temperature stress

Frontiers in Plant Science, 2022
Pinus massoniana Lamb. is the timber species with the widest distribution and the largest afforestation area in China, providing a large amount of timber, turpentine and ecological products.
Jingyu Lu, Hu Chen, Zhangqi Yang, Shuang-Wu Sun, Q. Luo, Junkang Xie, Jianhui Tan   +6 more
semanticscholar   +1 more source

Sampling rare switching events in biochemical networks

, 2004
Bistable biochemical switches are ubiquitous in gene regulatory networks and signal transduction pathways. Their switching dynamics, however, are difficult to study directly in experiments or conventional computer simulations, because switching events ...
C. Dellago, D. Frenkel, D. T. Gillespie, M. Mukamel, M. Ptashne, Patrick B. Warren, Pieter Rein ten Wolde, Rosalind J. Allen, T. B. Kepler   +8 more
core   +1 more source

Study the Mechanism of Gualou Niubang Decoction in Treating Plasma Cell Mastitis Based on Network Pharmacology and Molecular Docking

BioMed Research International, 2022
Objective Explore the potential molecular mechanisms behind the therapeutic functions of Gualou Niubang decoction (GLNBD) in the treatment of plasma cell mastitis (PCM) by network pharmacology and molecular docking.
Zhaojing Wu, Q. Yang, Hongbo Ma
semanticscholar   +1 more source

Toy Models and Statistical Mechanics of Subgraphs and Motifs of Genetic and Protein Networks [PDF]

arXiv, 2004
Theoretical physics is used for a toy model of molecular biology to assess conditions that lead to the edge of chaos (EOC) in a network of biomolecules. Results can enhance our ability to understand complex diseases and their treatment or cure.
arxiv