Results 51 to 60 of about 380,132 (123)

The C-value enigma and timing of the Cambrian explosion

open access: yes, 2008
The Cambrian explosion is a grand challenge to science today and involves multidisciplinary study. This event is generally believed as a result of genetic innovations, environmental factors and ecological interactions, even though there are many ...
Adami   +29 more
core   +1 more source

Computational core and fixed-point organisation in Boolean networks

open access: yes, 2006
In this paper, we analyse large random Boolean networks in terms of a constraint satisfaction problem. We first develop an algorithmic scheme which allows to prune simple logical cascades and under-determined variables, returning thereby the ...
A Pagnani   +17 more
core   +1 more source

Supplemental Data: Stochastic Gene Expression in a Lentiviral Positive Feedback Loop: HIV-1 Tat Fluctuations Drive Phenotypic Diversity [PDF]

open access: yesarXiv, 2006
Supplemental data for "Stochastic Gene Expression in a Lentiviral Positive Feedback Loop: HIV-1 Tat Fluctuations Drive Phenotypic Diversity" [q-bio.MN/0608002, Cell. 2005 Jul 29;122(2):169-82].
arxiv  

Does Collective Genetic Regulation exist? [PDF]

open access: yesarXiv, 2021
Does regulation in the genome use collective behavior, similar to the way the brain or deep neural networks operate? Here I make the case for why having a genomic network capable of a high level of computation would be strongly selected for, and suggest how it might arise from biochemical processes that succeed in regulating in a collective manner ...
arxiv  

Standardized network reconstruction of E. coli metabolism [PDF]

open access: yesarXiv, 2013
We have created a genome-scale network reconstruction of Escherichia coli metabolism. Existing reconstructions were improved in terms of annotation standards, to facilitate their subsequent use in dynamic modelling. The resultant network is available from EcoliNet (http://ecoli.sf.net/).
arxiv  

Rapid Analysis of Compounds from Piperis Herba and Piperis Kadsurae Caulis and Their Differences Using High-Resolution Liquid–Mass Spectrometry and Molecular Network Binding Antioxidant Activity

open access: yesMolecules
There is a serious mixing of Piperis Herba and Piperis Kadsurae Caulis in various parts of China due to the similar traits of lianas, and there is a lack of systematic research on the compound and activity evaluation of the two. Likewise, the differences
Dezhi Shi   +14 more
semanticscholar   +1 more source

Standardized network reconstruction of CHO cell metabolism [PDF]

open access: yesarXiv, 2013
We have created a genome-scale network reconstruction of chinese hamster ovary (CHO) cell metabolism. Existing reconstructions were improved in terms of annotation standards, to facilitate their subsequent use in dynamic modelling. The resultant network is available from ChoNet (http://cho.sf.net/).
arxiv  

Molecular networks involved in mouse cerebral corticogenesis and spatio-temporal regulation of Sox4 and Sox11 novel antisense transcripts revealed by transcriptome profiling

open access: yesGenome Biology, 2009
BackgroundDevelopment of the cerebral cortex requires highly specific spatio-temporal regulation of gene expression. It is proposed that transcriptome profiling of the cerebral cortex at various developmental time points or regions will reveal candidate ...
K. Ling   +12 more
semanticscholar   +1 more source

Michaelis-Menten Dynamics in Complex Heterogeneous Networks

open access: yes, 2005
Biological networks have been recently found to exhibit many topological properties of the so-called complex networks. It has been reported that they are, in general, both highly skewed and directed.
Albert   +42 more
core   +1 more source

Communication on the letter: "Evolutionary Conservation of Motif Constituents in the Yeast Protein Interaction Network." [PDF]

open access: yesarXiv, 2003
Former work on an application of order-disorder theory is recalled as a vehicle to add further development and significance to the recent paper on motifs in protein interactions.
arxiv  

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