In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Molecular phylogeny of the Tiliae group (<i>Inocybe</i> sect. <i>Marginatae</i>) and delimitation of the group with new discoveries. [PDF]
Fan YG +5 more
europepmc +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Molecular phylogeny and ecological diversity of endolichenic fungi inhabiting Acarospora schleicheri (Ach.) A. Massal, isolated from a Chilean Andean zone. [PDF]
Fernandez-Bunster G +2 more
europepmc +1 more source
Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Molecular phylogeny and morphometric divergence of native Korean wild mice (Mus musculus). [PDF]
Kim D +8 more
europepmc +1 more source
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia +9 more
wiley +1 more source
Taxonomic Revision and Molecular Phylogeny of the Genus <i>Morpheis</i> Hübner, [1820] (Lepidoptera: Cossidae). [PDF]
Naydenov AE +5 more
europepmc +1 more source
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
Molecular phylogeny of recognised Thai <i>Landouria</i> species (Gastropoda, Camaenidae), with descriptions of two new species. [PDF]
Nahok B, Chanlabut U, Tanmuangpak K.
europepmc +1 more source

