Results 61 to 70 of about 5,090,730 (289)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

MARVEL Analysis of the Measured High-resolution Spectra of CO Isotopologues

open access: yesThe Astrophysical Journal Supplement Series
Carbon monoxide is thought to be the second most abundant molecule in the Universe. This makes observation of both its parent isotopologue ( ^12 C ^16 O) and its stable isotopologues, ^13 C ^16 O, ^12 C ^18 O, ^12 C ^17 O, ^13 C ^18 O, and ^13 C ^17 O ...
Timur Grigorev   +5 more
doaj   +1 more source

Molecular Electronics: from Physics to Computing [PDF]

open access: yes, 2006
Even if Moore's Law continues to hold, it will take about 250 years to fill the performance gap between present-day computer and the ultimate computer determined from the laws of physics alone. Information processing technology in the post-CMOS era will likely consist of a heterogeneous set of novel device technologies that span a broad range of ...
Yongqiang Xue, Mark Ratner
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

MARVEL Analysis of the Measured High-resolution Spectra of 12C16O

open access: yesThe Astrophysical Journal Supplement Series
The Measured Active Rotational–Vibrational Energy Levels (MARVEL) algorithm is used to determine accurate empirical rotational–vibrational energy levels for the ground electronic state of the diatomic ^12 C ^16 O molecule.
Salman Mahmoud   +9 more
doaj   +1 more source

A study of New Physics searches with tritium and similar molecules

open access: yesEuropean Physical Journal C: Particles and Fields, 2020
Searches for New Physics focus either on the direct production of new particles at colliders or at deviations from known observables at low energies.
Wolfgang Gregor Hollik   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Rovibrational Transitions in HCl due to Collisions with H2: Spin-free and Hyperfine-resolved Transitions

open access: yesThe Astrophysical Journal
Hydrogen chloride (HCl) is a key repository of chlorine in the interstellar medium. Accurate determinations of its abundance are critical to assessing the chlorine elemental abundance and constraining stellar nucleosynthesis models.
Daniel Hoffman   +7 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Metal–Organic Frameworks in Modern Physics: Highlights and Perspectives

open access: yesAdvanced Science, 2019
Owing to the synergistic combination of a hybrid organic–inorganic nature and a chemically active porous structure, metal–organic frameworks have emerged as a new class of crystalline materials.
Yuri A. Mezenov   +4 more
doaj   +1 more source

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