Results 41 to 50 of about 3,951,961 (299)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
The global mass-invariant coupled-channel deperturbation model of the B ^2 Σ ^+ , A ^2 Π, and X ^2 Σ ^+ states of the CN radical, which reproduces the overall rovibronic term values of mutually perturbed levels with almost spectroscopic accuracy, has ...
S. V. Kozlov +5 more
doaj +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
A novel class of Mn(III) and Fe(III) complexes of L-tyrosine-based ligand has been synthesized and characterized through various analytical and spectroscopic techniques.
Biju Bennie Rajaretnam +4 more
doaj +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
SPECTROSCOPIC CONSTANTS OF $CS_{2}$
Author Institution: Department of Physics, College of William and Mary; Laboratoire de Physique Mol\'{e}culaire et Applictions, CNRS, B\""{a}t. 350 Universit\'{e} de Paris-Sud; RAO Department of Physics, Ohio State UniversityThe Fourier spectrometer of ...
Loughman, Robert +5 more
core +1 more source
Cyclopropenethione falls into the class of complex organic molecules but has not yet been observed in the interstellar medium or any circumstellar disks. However, its existence is very likely, and thus this study provides high-level ab initio predictions,
Subhasish Das, Guntram Rauhut
doaj +1 more source
In this study, bovine serum albumin (BSA), a model transport protein, is shown to interact with two pyrrolidinium based ionic liquids (ILs), namely, 1-hexyl-1-methyl pyrrolidinium bromide [PyrC6]Br−and 1-dodecyl-1-methyl pyrrolidinium bromide [PyrC12]Br−.
Aashima Anand +2 more
doaj +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Raman spectroscopic determination of the acidity constants of salicylaldoxime in aqueous solution
A sensitive and efficient method for the determination of acidity constants of salicylaldoxime (SALO) (2-hydroxybenzaldehyde oxime), using both Raman spectroscopic and potentiometric methods, at 30 °C in 50 (wt/wt) of ethanol-water mixture and at the ...
H. G. M. Edwards (8726859) +3 more
core +2 more sources

