Results 211 to 220 of about 2,165,084 (288)

Molecular Structure of Omniphobic, Surface-Grafted Polydimethylsiloxane Chains. [PDF]

Small
Khatir B, Lin A, Vuong TV, Serles P, Shayesteh A, Hsu NSY, Sinton D, Tran H, Master ER, Filleter T, Golovin K.   +10 more
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

A multi-dimensional computational framework of drug-induced hepatotoxicity: integrating molecular structure features with disease pathogenesis. [PDF]

Brief Bioinform
Zhong H, Wang J, Liu X, Wei X, Zhou C, Zou T, Han X, Mo L, Qin W, Zhang Y.   +9 more
europepmc   +1 more source

Relationship between retention behavior and molecular structure in HPLC. Correlation between solubility parameter and molecular properties

, 1994
Zhao Sun, M. C. Liu, Zenan Hu
openalex   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Constitutive relationship between pore-permeability and molecular structure of bituminous coal based on the Kozeny-Carman equation. [PDF]

PLoS One
Pang M, Zhang T, Li L, Zhang T, Pan H.
europepmc   +1 more source

Surface Structure of Quaternary Ammonium Based Ionic Liquid Studied Using Molecular Dynamics Simulation

, 2015
Seiji Katakura, Naoya Nishi, Kazuya Kobayashi, Ken‐ichi Amano, Tetsuo Sakka   +4 more
openalex   +2 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Hybridization of SMILES and chemical-environment-aware tokens to improve performance of molecular structure generation. [PDF]

Sci Rep
Han H, Yeom MS, Choi S.
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source