Results 221 to 230 of about 19,367,956 (387)

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Molecular structure and enzymatic mechanism of the human collagen hydroxylysine galactosyltransferase GLT25D1/COLGALT1. [PDF]

Nat Commun
De Marco M, Rai SR, Scietti L, Mattoteia D, Liberi S, Moroni E, Pinnola A, Vetrano A, Iacobucci C, Santambrogio C, Colombo G, Forneris F.   +11 more
europepmc   +1 more source

XLIX.—Researches on the relation between the molecular structure of carbon compounds and their absorption-spectra. (Part IX.) On isomeric cresols, dihydroxybenzenes, and hydroxybenzoic acids [PDF]

, 1888
Walter Noel Hartley
openalex   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Optimization of Insulation Structure Design for Enameled Wires Based on Molecular Structure Design. [PDF]

Polymers (Basel)
Yu Y, Li S, Weng L, Zhang X, Liu L, Chen Q.   +5 more
europepmc   +1 more source

The molecular structures of carbon and silicon tetrafluorides.

, 1938
C. R. Bailey, J. B. Hale, J. W. Thompson
openalex   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

VisionMol: a novel virtual reality tool for protein molecular structure visualization and manipulation. [PDF]

Bioinformatics
Wang X, Zhuang Y, Liang W, Wen H, Cai Z, He Y, Su Y, Qin W, Cai Y, Liang L, Huang B.   +10 more
europepmc   +1 more source

Molecular Structures of Dodecafluoro-n-Pentane, Hexadecafluoro-n-Heptane, and Dodecafluoro-Isopentane. [PDF]

, 1952
Otto Bastiansen, Eva Hadler, Å. Åkerström, Ernst Finsnes, Jörgine Stene Sörensen, Nils Andreas Sörensen   +5 more
openalex   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source