Results 181 to 190 of about 717,994 (294)

FOXO1 phosphorylation as a context-dependent molecular switch in cancer: from mechanisms to precision therapy. [PDF]

World J Surg Oncol
Wang J, Ren K, Wang X, Zhang S, Zhao J.
europepmc   +1 more source

Molecular switch to regulate salt tolerance in rice. [PDF]

Plant Cell, 2023
Molla KA.
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Apelin signaling acts as a molecular switch between endothelial and hematopoietic stem cell fates. [PDF]

EMBO Rep
Eberlein J, Groos N, Shrestha Duwal N, Sugden WW, North TE, Helker CSM.   +5 more
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

An AuNP-labeled triple-helix molecular switch for ultrasensitive, on-site detection of tetracycline in milk via fiber-optic localized surface plasmon resonance biosensing. [PDF]

Food Chem X
Situ X, Li J, Zhang Y, Yan H.
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

TERT expression in human prostate tissue reveals a potential molecular switch in benign prostatic hyperplasia progression. [PDF]

World J Urol
Xu Y, Hu S, Berger L, Nicola P, Weinhold P, Tamalunas A, Stief CG, Hennenberg M, Keller P.   +8 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Correction: Exosome-mediated miRNA delivery: a molecular switch for reshaping neuropathic pain therapy. [PDF]

Front Mol Neurosci
Wei Z, Guo C, Zhou H, Wu Y, Zhou X, Chen J, Li F.   +6 more
europepmc   +1 more source