Results 1 to 10 of about 5,964,458 (191)
A massively parallel screening platform for converting aptamers into molecular switches [PDF]
Nature Communications, 2023 Aptamer-based molecular switches that undergo a binding-induced conformational change have proven valuable for a wide range of applications, such as imaging metabolites in cells, targeted drug delivery, and real-time detection of biomolecules.
Alex M. Yoshikawa +7 more
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Molecular Switches—Tools for Imparting Control in Drug Delivery Systems [PDF]
Frontiers in Chemistry, 2022 Cancer is a globally prevalent cause of premature mortality. Of growing interest is the development of novel anticancer therapies and the optimisation of associated risks.
Owen Fitzmaurice +2 more
doaj +3 more sources
Synthetic molecular switches driven by DNA-modifying enzymes [PDF]
Nature CommunicationsTaking inspiration from natural systems, in which molecular switches are ubiquitous in the biochemistry regulatory network, we aim to design and construct synthetic molecular switches driven by DNA-modifying enzymes, such as DNA polymerase and nicking ...
Hong Kang, Yuexuan Yang, Bryan Wei
doaj +3 more sources
Recent Advances in Fuel‐Driven Molecular Switches and Machines [PDF]
ChemistryOpen, 2022 The molecular switches and machines arena has entered a new phase in which molecular machines operate under out‐of‐equilibrium conditions using appropriate fuel.
Renitta Benny +3 more
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MicroRNAs as Molecular Switches in Macrophage Activation [PDF]
Frontiers in Immunology, 2019 The efficacy of macrophage- mediated inflammatory response relies on the coordinated expression of key factors, which expression is finely regulated at both transcriptional and post-transcriptional level. Several studies have provided compelling evidence
Graziella Curtale +4 more
doaj +3 more sources
Unfolding molecular switches for salt stress resilience in soybean: recent advances and prospects for salt-tolerant smart plant production. [PDF]
Front Plant Sci, 2023 The increasing sodium salts (NaCl, NaHCO3, NaSO4 etc.) in agricultural soil is a serious global concern for sustainable agricultural production and food security.
Feng C +11 more
europepmc +2 more sources
Smart molecular crystal switches
Smart MoleculesThe multifaceted switches are part of our everyday life from the macroscopic to the molecular world. A molecular switch operating in the solution and in the crystalline state is very different.
Ian Cheng‐Yi Hou +3 more
doaj +2 more sources
Environmentally Sensitive Molecular Switches Drive Poplar Phenology
Frontiers in Plant Science, 2018 Boreal and temperate woody perennials are highly adapted to their local climate, which delimits the length of the growing period. Moreover, seasonal control of growth-dormancy cycles impacts tree productivity and geographical distribution.
Jay P. Maurya +3 more
doaj +2 more sources
International Journal of Molecular Sciences, 2020 Riboswitches and toehold switches are considered to have potential for implementation in various fields, i.e., biosensing, metabolic engineering, and molecular diagnostics.
Tin Hoang Trung Chau +2 more
exaly +2 more sources
Molecules, 2017 Design of rotatory molecular switches based on extremely stable sandwich organometallic complexes ferrocene and bis(dicarbollide) complexes of transition metals is reviewed.
Igor B Sivaev
exaly +2 more sources