Results 231 to 240 of about 3,518,193 (347)

Human Immunodeficiency Virus-Specific Circulating CD8 T Lymphocytes Have Down-Modulated CD3ζ and CD28, Key Signaling Molecules for T-Cell Activation

, 2000
Linda A. Trimble, Premlata Shankar, Mark Patterson, Johanna P. Daily, Judy Lieberman   +4 more
openalex   +2 more sources

Ion channels, guidance molecules, intracellular signaling and transcription factors regulating nervous and vascular system development [PDF]

, 2015
Tenpei Akita, Tatsuro Kumada, Sei‐ichi Yoshihara, Joaquim Egea, Satoru Yamagishi   +4 more
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

¹⁷O Chemical Shifts in Water. [PDF]

J Phys Chem A
de Dios AC.
europepmc   +1 more source

Nonequilibrium mechanism of transcription termination from observations of single RNA polymerase molecules

, 1999
Hong Yin, Irina Artsimovitch, Robert Landick, Jeff Gelles   +3 more
openalex   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

The Omics Molecule Extractor: A Web Application for the Selection of Potential Biomarker Panels. [PDF]

J Proteome Res
Lange E, Schallert K, Schwerdt J, Ghosh S, Hentschel A, Reinders Y, Heyer R.   +6 more
europepmc   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Molecular time machines unleashed: small-molecule-driven reprogramming to reverse the senescence. [PDF]

Stem Cells Transl Med
Tang C, Zhang Z, Yang C, Li L, Li J, Cheng X, Zhou W, Lin Y, Zeng L, Zhang L.   +9 more
europepmc   +1 more source

Challenges in the use of atomistic simulations to predict solubilities of drug-like molecules [PDF]

, 2019
Guilherme Duarte Ramos Matos, David L. Mobley   +1 more
openalex   +1 more source