Results 21 to 30 of about 3,841,010 (347)
Research Advances in Molecular Regulatory Mechanism of Chordoma
Zhongliu Fangzhi Yanjiu, 2019 Chordoma is a rare primary malignant bone tumor derived from notochord remnants. Due to its strong local invasiveness and chemotherapy resistance, chordoma has a high local recurrence rate and poor prognosis.
LIANG Chen, YANG Chenlong, LIU Xiaoguang
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Cell, 2007 "Working memory" is used for the transient storage of information in the brain. In this issue of Cell, Wang et al. (2007) now reveal how a series of molecular events involving alpha2A-adrenoceptors and a class of ion channels gated by cAMP tune the responses of neural circuits that function in working memory in mammals.
Ranulfo Romo, Emilio Salinas
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How the Toxin got its Toxicity
Frontiers in Pharmacology, 2020 Venom systems are functional and ecological traits, typically used by one organism to subdue or deter another. A predominant subset of their constituent molecules—“toxins”—share this ecological function and are therefore molecules that mediate ...
Timothy N. W. Jackson, Ivan Koludarov
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Ultrafast dynamics in molecular ions following UV and XUV excitation: a perspective
Advances in Physics: X, 2022 Gas phase experiments combined with ultrafast technologies can provide information on the intrinsic properties of molecular systems at picosecond, femtosecond, or even attosecond timescales.
Marius Hervé +4 more
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Magnetic hysteresis up to 80 kelvin in a dysprosium metallocene single-molecule magnet
Science, 2018 Breaking through the nitrogen ceiling Single-molecule magnets could prove useful in miniaturizing a wide variety of devices. However, their application has been severely hindered by the need to cool them to extremely low temperature using liquid helium ...
Fu-Sheng Guo +5 more
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Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska, 2013 This article describes cluster model of gaseous materials and prospects of using the model. Equations set for the calculation of different sizes clusters concentrations are presented. The authors produce numerical solution of the equation set. Results of
Alexey Bublikov +2 more
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Flavone Enhances Dengue Virus Type-2 (NGC Strain) Infectivity and Replication in Vero Cells
Molecules, 2012 This study investigates the effects of 2-phenyl-1-benzopyran-4-one (flavone) on DENV-2 infectivity in Vero cells. Virus adsorption and attachment and intracellular virus replication were investigated using a foci forming unit assay (FFUA) and ...
Keivan Zandi +7 more
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Cooperation of Oligodeoxynucleotides and Synthetic Molecules as Enhanced Immune Modulators
Frontiers in Nutrition, 2019 Unmethylated cytosine–guanine dinucleotide (CpG) motifs are potent stimulators of the host immune response. Cellular recognition of CpG motifs occurs via Toll-like receptor 9 (TLR9), which normally activates immune responses to pathogen-associated ...
Shireen Nigar, Takeshi Shimosato
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Generating Focused Molecule Libraries for Drug Discovery with Recurrent Neural Networks
ACS Central Science, 2017 In de novo drug design, computational strategies are used to generate novel molecules with good affinity to the desired biological target. In this work, we show that recurrent neural networks can be trained as generative models for molecular structures ...
Marwin H. S. Segler +3 more
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Química Nova, 1997 The concepts of molecule and of molecular structure are so central to understand chemical phenomena that seems to be no doubt about the uniqueness of its meanings. Nevertheless, the idea that the world exhibits a multiform structure and that to different
Eduardo Fleury Mortimer
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