Results 291 to 300 of about 3,518,193 (347)

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Controlled magnetic bistability of a helical non-Kekulé hydrocarbon on a Au(111) surface. [PDF]

Nat Commun
Karbasiyoun M, Di Giovannantonio M, Biswas K, Écija D, Blacque O, Catarina G, Krane N, Pignedoli CA, Ruffieux P, Urgel JI, Fasel R, Juríček M.   +11 more
europepmc   +1 more source

Unraveling single-molecule reactions via multiplexed in-situ DNA sequencing

Hazra JP, Andrews R, Turner P, Zhao Q, Steuer H, El-Sagheer AH, Mazumder A, El Sayyed H, Kümmerlin M, Brown T, Kapanidis AN.   +10 more
europepmc   +1 more source

An effective fragment-based dual conditional diffusion framework for molecular generation. [PDF]

Brief Bioinform
Chen H, Shen Y, Li J, Zhao W.
europepmc   +1 more source

Toward the universality of the Caldeira-Leggett oscillator bath as a model for quantum environments I. [PDF]

Sci Rep
Halataei SMH.
europepmc   +1 more source

Multi-state detection and spatial addressing in a microscope for ultracold molecules. [PDF]

Nat Commun
Mortlock JM, Raghuram AP, Maddox BP, Gregory PD, Cornish SL.   +4 more
europepmc   +1 more source

RMPore: a comprehensive database of single-molecule RNA modifications detected by Nanopore direct RNA sequencing. [PDF]

Nucleic Acids Res
Lin Z, Bao X, Zhang L, Huang Y, Li H, Liu W, Ren J, Zuo Z, Hu K.   +8 more
europepmc   +1 more source

A technique to create hydrogels with tethered concentration gradients of molecules <i>in vitro</i>.

Soft Matter
O'Shea TC, Salem A, Schultz KM.
europepmc   +1 more source