Results 151 to 160 of about 28,903,831 (255)

Efficacy and Safety of Subcutaneous Anifrolumab in Systemic Lupus Erythematosus: the Randomized, Phase 3, TULIP‐SC Study

Arthritis &Rheumatology, Accepted Article.
Objective The multinational, phase 3, double‐blind, placebo‐controlled TULIP‐SC trial evaluated the efficacy and safety of subcutaneous anifrolumab in adults who have moderate‐to‐severe SLE activity, despite receiving standard therapy. Methods Adults with SLE received subcutaneous anifrolumab 120 mg or placebo once weekly for 52 weeks (1:1 ...
Susan Manzi, Ian N. Bruce, Eric F. Morand, Richard Furie, Yoshiya Tanaka, Kenneth C. Kalunian, Anca Askanase, Patricia Puzio, Emon Khan, Jenny Wissmar, Michael Song, Catharina Lindholm, The TULIP‐SC investigators   +12 more
wiley   +1 more source

A review on spectral data preprocessing techniques for machine learning and quantitative analysis. [PDF]

iScience
Yan C.
europepmc   +1 more source

Measuring the Impact: MRI Response of Sacroiliac Joints to TNF Inhibitors in Youth with Axial Disease

Arthritis &Rheumatology, Accepted Article.
Objective To evaluate the timeline for resolution of sacroiliac joint (SIJ) inflammation, changes in structural lesions, and their correlation with patient‐reported outcomes in youth with axial juvenile spondyloarthritis (axJSpA) initiating TNF inhibitor (TNFi).
Timothy G. Brandon, Rui Xiao, Daniel J. Lovell, Edward Oberle, Matthew L. Stoll, Nancy A. Chauvin, Michael L. Francavilla, Walter P. Maksymowych, Pamela F. Weiss   +8 more
wiley   +1 more source

Medical students' initial experiences of the dissection room and interaction with body donors: A qualitative study of professional identity formation, educational benefits, and the experience of Pasifika students

Anatomical Sciences Education, EarlyView.
Abstract The first experience of medical students in the dissecting room (DR) likely influences professional identity formation (PIF). Sparse data exist exploring how exposure to the DR and body donors without undertaking dissection influences PIF, or how culture may influence this experience.
Jacob Madgwick, Lynley Anderson, Jon Cornwall   +2 more
wiley   +1 more source

Is there evidence for pelvic floor muscle relaxation training in nonneurogenic female bladder outlet obstruction?-A narrative review. [PDF]

Neurourol Urodyn
Bø K.
europepmc   +1 more source

Optimizing Measurement of Communication in Autistic Children and Their Caregivers: Dependability of the Caregiver‐Child Interaction

Autism Research, EarlyView.
ABSTRACT Despite widespread use of caregiver‐child interactions (CCX) to evaluate outcomes in autism interventions, little research has examined the dependability of this measure. This study applied generalizability theory to determine optimal conditions for dependable assessment of child communication and caregiver implementation of communication ...
Lauren H. Hampton, Anna‐Mari Fall, Jerrica Butler, Greg Roberts, Younghwa Noh   +4 more
wiley   +1 more source

Population pharmacokinetics and exposure–response analysis of durvalumab in patients with resectable stage II to IIIB (N2) NSCLC in the phase III AEGEAN study

British Journal of Clinical Pharmacology, EarlyView.
Aims In the AEGEAN study, perioperative durvalumab plus platinum‐based neoadjuvant chemotherapy for patients with resectable stage II to IIIB (N2) non‐small‐cell lung cancer (NSCLC) demonstrated a favourable benefit–risk profile. This study evaluated population pharmacokinetics (PopPK) and exposure–response (ER) relationships of durvalumab in patients ...
Xiaoying Zhao, Junjie Ding, Jiajia Zhao, Ling Zhang, Aburough Abegesah, Yu‐qian Zhang, Cathy O'Brien, Gary J. Doherty, Allen C. Chen, KyoungSoo Lim, Song Ren, Peiming Ma, Diansong Zhou   +12 more
wiley   +1 more source

COVID-19 and urban vulnerability in India. [PDF]

Habitat Int, 2020
Mishra SV, Gayen A, Haque SM.
europepmc   +1 more source

Evaluation of the Medicines and Healthcare products Regulatory Agency's introduction of a risk‐proportionate approach for clinical trials: An analysis of 4617 applications assessed between September 2023 and August 2024

British Journal of Clinical Pharmacology, EarlyView.
Aims The Medicines and Healthcare products Regulatory Agency (MHRA) introduced a risk‐proportionate approach to assess clinical trial applications for authorisation in August 2023. This study evaluates the impact of this approach on the timelines for reviewing proposals.
Andrea Manfrin, Kingyin Lee, Crina Cacou, James Pound, Anthony Harnden, June Raine, Munir Pirmohamed   +6 more
wiley   +1 more source

Global Solutions of the One-Dimensional Compressible Euler Equations with Nonlocal Interactions via the Inviscid Limit. [PDF]

Arch Ration Mech Anal
Carrillo JA, Chen GG, Yuan D, Zatorska E.   +3 more
europepmc   +1 more source