Results 161 to 170 of about 28,903,831 (255)

Effects of Renal and Hepatic Impairment on the Pharmacokinetics of Zilurgisertib

British Journal of Clinical Pharmacology, EarlyView.
Aim Small‐molecule activin receptor‐like kinase‐2 inhibitor zilurgisertib (INCB000928) is under investigation in a pivotal trial for the treatment of fibrodysplasia ossificans progressiva (FOP), an ultrarare genetic condition. This analysis assessed effects of renal and hepatic impairment on zilurgisertib pharmacokinetics.
Yan‐ou Yang, Yunlan Fang, Phillip Wang, Xiang Liu, Jay Getsy, Kevin Rockich   +5 more
wiley   +1 more source

Stopper vs. Singular Controller Games With Degenerate Diffusions. [PDF]

Appl Math Optim
Bovo A, De Angelis T, Palczewski J.
europepmc   +1 more source

Activism as education in and through the youth climate justice movement

British Educational Research Journal, EarlyView.
Abstract Young people worldwide are increasingly participating in a global movement for climate justice, yet to date, little research has examined how youth climate justice activists conceive of and experience activism as education. The present study used in‐depth, semi‐structured interviews with 16 US climate justice activists (aged 15–17) to address ...
Carlie D. Trott
wiley   +1 more source

The Case of the Missing Green Iguana Predators: Reviews of Ecological Literature Should Go Beyond Google Scholar

The Bulletin of the Ecological Society of America, EarlyView.
Abstract Knowing about species interactions is essential for ecological research, conservation efforts, resource management, and maintaining healthy ecosystems, but many of these, such as reports of predation, may not always be published in easily located resources—if they are published at all.
Matthijs P. van den Burg, Hinrich Kaiser
wiley   +1 more source

Affinity Peptides With pH Sensitivity for the Enrichment of CD38+ Cells

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The selective enrichment of cell populations based on surface markers is critical for the advancement of gene and cell therapies. Current antibody‐based cell isolation methods, such as fluorescence‐ and magnetic‐activated cell sorting (FACS and MACS), offer high specificity but are limited by scalability, cost, and potential adverse effects on
Gabrielle Rusch, Mickael Meyer, I. Mohamed Irfan, Carson Huber, Joseph Burclaff, Scott T. Magness, Stefano Menegatti, Michael Daniele   +7 more
wiley   +1 more source

Targeting MAT2A synergistically induces DNA damage in osteosarcoma cells through EZH2-mediated H3K27me3 modification. [PDF]

J Orthop Translat
Yang B, Wang H, Tao Y, Yang X, Mu H, Yang L, Jiang Y, Wang Z, Zhang R, Cai Z, Yang C, Zuo D, Hua Y, Sun W.   +13 more
europepmc   +1 more source

Adaptive Algal Cultivation Enabled by a Monthly Biomass Forecasting System

Biotechnology and Bioengineering, EarlyView.
The developed monthly algal forecasting system used to predict biomass production for two algal strains (A and B) at two pond water depths (low and high). The highest predicted production, achieved with strain A at a low pond water depth, is selected as the cultivation strategy to guide the next month's algal growth.
Hongxiang Yan, Song Gao, Mark S. Wigmosta, Andre M. Coleman, Ning Sun, Michael H. Huesemann   +5 more
wiley   +1 more source

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

BMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu, Chung Yin Matthew Cheung, Liling Liu, Hoi Pan Harry Cheung, Kam Yu Tam, Dai Fei Elmer Ker, Sarah H. Cartmell, Chuanbin Mao, Zhiyong Zhang, Dan Michelle Wang   +9 more
wiley   +1 more source

Toward personalized healthcare: Advances in two‐dimensional nanomaterial‐based flexible electrochemical sensors for physiological monitoring

BMEMat, EarlyView.
This review provides an overview of the properties, composites and application of two‐dimensional (2D) nanomaterials for wearable electrochemical biosensors. Also, the challenges and future prospects of utilizing 2D nanomaterials in wearable electrochemical biosensor applications are discussed.
Kou Zhang, Lu Han, He‐Qing Cai, Xin‐Yu Xue, Yi‐Fei Song, Wu‐Lin Xin, Ying‐Ze Wang, Peng Liu, Juan Liu   +8 more
wiley   +1 more source

A review of the historic and present ecological role of aquatic and shoreline wood, from forest to deep sea

Biological Reviews, EarlyView.
ABSTRACT The ecology of forests, their losses, and terrestrial wood decomposition dynamics have been intensively studied and reviewed. In the aquatic realm, reviews have concentrated on large wood (LW) in rivers and the transition from freshwater to marine environments in the Pacific Northwest of North America. However, a comprehensive global synthesis
Jon Dickson, Ellen Wohl, Laura L. Govers, Oscar Franken, Tjeerd J. Bouma, Han Olff, Britas Klemens Eriksson, Maryann S. Watson, Luísa M.S. Borges, Tjisse van der Heide   +9 more
wiley   +1 more source