Results 161 to 170 of about 408,174 (388)
The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity
FEBS Open Bio, EarlyView.We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo +11 more
wiley +1 more source
Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3
FEBS Open Bio, EarlyView.PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno +12 more
wiley +1 more source
Single grid accelerator for an ion thrustor [PDF]
, 1973 A single grid accelerator system for an ion thrustor is discussed. A layer of dielectric material is interposed between this metal grid and the chamber containing an ionized propellant for protecting the grid against sputtering ...
Margosian, P. M., Nakanishi, S.
core +1 more source
THE DETERMINATION OF VANADIUM, MOLYBDENUM, CHROMIUM AND NICKEL IN STEEL. [PDF]
, 1908 Andrew Alexander Blair
openalex +1 more source
The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions
FEBS Open Bio, EarlyView.Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh +2 more
wiley +1 more source
Process Mineralogy of Flotation Products of a Copper-molybdenum Ore in Jiama, Xizang
Kuangchan zonghe liyongThe process mineralogy was studied on hornstone and skarn copper-molybdenum ores and the copper and molybdenum concentrates was obtained by separating flotationin Jiama, Xizang. The research shows that the hornstone copper-molybdenum ore contains Cu 0.38%
Jinming GUO +6 more
doaj +1 more source
Molybdenum in the Growth and Metabolism of Chlorella [PDF]
, 1954 J. F. Loneragan, Daniel I. Arnon
openalex +1 more source
FEBS Open Bio, EarlyView.Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto +5 more
wiley +1 more source
Rapid chemical test for the identification of chromium-molybdenum steel [PDF]
This note describes a simple, rapid, qualitative test which can be applied to solutions of drilling or chips for the identification of chromium-molybdenum steel.
Redmond, John C
core +1 more source