Lactate Homeostasis Disruption Potentiates TACE‐Immunotherapy in Hepatocellular Carcinoma
Lactate homeostasis is disrupted through spatially coordinated extracellular neutralization and intracellular acidification, triggering calcium overload, mitochondrial dysfunction, and immunogenic cell death. This metabolic reprogramming alleviates the immunosuppressive tumor microenvironment and enhances immune checkpoint blockade, providing a ...
Minjiang Chen +12 more
wiley +1 more source
Experimental and Mechanistic Study on Flotation Separation of Chalcopyrite and Molybdenite Using the Novel Depressant 2-Mercapto-6-Methylpyrimidin-4-ol. [PDF]
Lv X, Luo A, Tong X, Chen J, Jian S.
europepmc +1 more source
Targeted surface chemical modification prevents the accumulation of advanced glycation end products (AGEs) on implant surfaces, attenuates inflammation and fibrosis, effectively restores angiogenic activity, and improves osseointegration under diabetic conditions.
Thien Ngoc Le +13 more
wiley +1 more source
Assessment of the Potential for Producing Geopolymer-Based Granulates as a Substitute for Natural Aggregates. [PDF]
Cempa M, Korol J, Klupa A.
europepmc +1 more source
Pathogenic Acinetobacter baumannii scavenges metal ions as nutritional elements to survive within the host. This study demonstrates that molybdopterin synthase is essential for pathogenesis and full virulence during infection. Molybdopterin synthase subunit MoaE constitutes an intrinsically disordered C‐terminal histidine rich tail, which mediates ...
Min Jiao +13 more
wiley +1 more source
Genome-resolved metagenomics and evolutionary analysis reveal conserved metabolic adaptations in extremophile communities from a copper mining tailing. [PDF]
Rojas MA +11 more
europepmc +1 more source
Study on the Properties of All-Solid Waste Fluidized Filling Materials Applied to Mine Void Area Filling Engineering. [PDF]
Lu Y +6 more
europepmc +1 more source
Study on the Selective Inhibition of FeSO<sub>4</sub>-NaH<sub>2</sub>PO<sub>4</sub> in Sphalerite-Pyrite Flotation Separation. [PDF]
Zhang Z, Xiao J, Liu S, Xiao P, Cao H.
europepmc +1 more source
Molybdenum-Induced Oxidative and Inflammatory Injury and Metabolic Pathway Disruption in Goat Pancreas. [PDF]
Li L, Ran Y, Shen X.
europepmc +1 more source

