Results 151 to 160 of about 7,057,467 (296)

Moment generating function of a first hitting place for the integrated Ornstein-Uhlenbeck process

open access: yes
We consider the two-dimensional process (x(t),y(t)), where y(t)=dx(t)/dt is an Ornstein-Uhlenbeck process, Let T be the smallest t for which y(t) = [upsilon].
Lefebvre, Mario
core  

Risk aversion and uncertainty in cost-effectiveness analysis: the expected-utility, moment-generating function approach

open access: yes
The availability of patient-level data from clinical trials has spurred a lot of interest in developing methods for quantifying and presenting uncertainty in cost-effectiveness analysis (CEA).
Elamin H. Elbasha
core   +1 more source

On convergence of moment generating functions

open access: yes
Mukherjea et al. [Mukherjea, A., Rao, M., Suen, S., 2006. A note on moment generating functions. Statist. Probab. Lett. 76, 1185-1189] proved that if a sequence of moment generating functions Mn(t) converges pointwise to a moment generating function M(t)
Ushakov, N.G., Ushakov, V.G.
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

The Joint Moment Generating Function of Quadratic Forms in Multivariate Autoregressive Series

open access: yes
Let ( X1 ) be a discrete multivariate Gaussian autoregressive process of order 1. The paper derives the exact finite-sample joint moment generating function (m.g.f.) of the three quadratic forms constituting the sufficient statistic of the process.
Larsson, Rolf, Abadir, Karim M.
core  

Estimation of the location parameter under LINEX loss function: multivariate case

open access: yes
Moment generating function, Empirical Bayes, LINEX loss function, Restricted model,
M. Arashi, S. Tabatabaey
core   +1 more source

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