Results 211 to 220 of about 60,178 (261)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Quantum squeezing amplification with a weak Kerr nonlinear oscillator. [PDF]

Nat Commun
Cai Y, Deng X, Zhang L, Ni Z, Mai J, Huang P, Zheng P, Hu L, Liu S, Xu Y, Yu D.   +10 more
europepmc   +1 more source

Coupled aerodynamic-electromagnetic modeling for RCS estimation of million-scale chaff clouds with arbitrarily curved 3D geometries. [PDF]

Sci Rep
Lee CH, Jang B, Kwon K, Kim KT, Na DY.
europepmc   +1 more source

Statistical inference and applications of a new transforming weibull distribution. [PDF]

Sci Rep
Li X, Gong Q, Chen T.
europepmc   +1 more source

Evolving Paradigms in Lumbar Disc Herniation: From Prediction to Precision Surgery. [PDF]

Neurospine
Vadalà G, AO Spine Knowledge Forum Degenerative.   +1 more
europepmc   +1 more source

Reducing phenotype-structured partial differential equations models of cancer evolution to systems of ordinary differential equations: a generalised moment dynamics approach. [PDF]

J Math Biol
Villa C, Maini PK, Browning AP, Jenner AL, Hamis S, Cassidy T.   +5 more
europepmc   +1 more source

Benchmarking physics-inspired machine learning models for transition metal complexes with diverse charge and spin states.

Digit Discov
Cho Y, Briling KR, Calvino Alonso Y, Laplaza R, Corminboeuf C.   +4 more
europepmc   +1 more source