Results 121 to 130 of about 84,435 (298)

Wireless magnetic-based closed-loop control of self-propelled microjets.

PLoS ONE, 2014
In this study, we demonstrate closed-loop motion control of self-propelled microjets under the influence of external magnetic fields. We control the orientation of the microjets using external magnetic torque, whereas the linear motion towards a ...
Islam S M Khalil, Veronika Magdanz, Samuel Sanchez, Oliver G Schmidt, Sarthak Misra   +4 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Energy-second-moment map analysis as an approach to quantify the irregularity of Hamiltonian systems

A different approach will be presented that aims to scrutinize the phase-space trajectories of a general class of Hamiltonian systems with regard to their regular or irregular behavior.
Redelbach, Andreas, Struckmeier, Jürgen
core   +2 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

A moment map picture of relative balanced metrics on extremal K\"ahler manifolds

, 2020
26 pages. Corrections in the proof of Proposition 5.2, and other minor modifications in the expositionInternational audienceWe give a moment map interpretation of some relatively balanced metrics. As an application, we extend a result of S. K.
Tipler, Carl, Sano, Yuji
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Multi-Source Remote Sensing Image Matching in Mountainous Areas Based on Spatial Structure Features

IEEE Access
The multi-source remote sensing images in mountainous areas are affected by variations in resolution, imaging angles, and atmospheric conditions, resulting in significant nonlinear radiation and geometric distortion discrepancies among the images, which ...
Xiaojuan Liu, Feng Jiang, Qiaoling Zhang, Shenghui Fang, Siyu Zhang, Yuyan Yan, Ping Xiang, Qiang Xiong   +7 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

D2G-Mamba: A Distribution-to-Geometry Alignment Paradigm for Efficient Cross-Modal Object Detection

IEEE Access
Reliable perception in adverse illumination and weather is essential for applications such as autonomous driving. Visible-infrared fusion mitigates single-sensor failure modes, yet semantic misalignment between modalities and the quadratic cost of ...
Shaowen Xue, Zhi Zhang, Yile Zhang, Xinrui Tong   +3 more
doaj   +1 more source