Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Mechanical mechanism study of upper airway collapse and twin block treatment in a patient with mandibular retrognathia using fluid-structure interaction simulation. [PDF]
Wang J, Han Y, Chen S, Li M, Lee C.
europepmc +1 more source
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Geometry-Driven Control of Linear and Nonlinear Optical Responses in <i>p</i>‑Nitroaniline: Insights into Structure-Property Relationships and Thermal Robustness. [PDF]
Manzoni V +5 more
europepmc +1 more source
A Residue Formula for SU(2)-valued Moment Maps [PDF]
Olga Plamenevskaya
openalex +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Mechanical behavior of reservoir bank slope-pile-sheet structures under reservoir operation: Field monitoring and numerical simulation analysis. [PDF]
Cai Z +7 more
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Observation of giant dipole moments of interlayer excitons via layer engineering. [PDF]
Zhu J, Liang T, Shen F, Chen Z, Xu J.
europepmc +1 more source

