Results 91 to 100 of about 205,854 (269)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

On order statistics from the Gompertz–Makeham distribution and the Lambert W function

Mathematical Modelling and Analysis, 2013
The aim of this paper is twofold. First, we show that the expected value of the minimum order statistic from the Gompertz-Makeham distribution can be expressed in closed form in terms of the incomplete gamma function.
Pedro Jodra
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Predicting moment-to-moment attentional state

NeuroImage, 2014
Although fluctuations in sustained attention are ubiquitous, most psychological experiments treat them as noise, averaging performance over many trials. The current study uses multi-voxel pattern analysis (MVPA) to decode whether, on each trial of a cognitive task, participants are in an optimal or suboptimal attentional state.
Monica D. Rosenberg, Emily S. Finn, R. Todd Constable, Marvin M. Chun   +3 more
openaire   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Heterogeneous Responses of Energy and Non-Energy Assets to Crises in Commodity Markets

Energies
In this study, we investigate the heterogeneity in energy and non-energy commodities by analyzing their four realized moments: returns, realized volatility, realized skewness and realized kurtosis.
Dimitrios Vortelinos, Angeliki Menegaki, Ioannis Passas, Alexandros Garefalakis, Georgios Viskadouros   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Mathematical Modeling of the Optimal Cost for the Design of Strap Combined Footings

Mathematics
This paper presents a novel mathematical model to determine the minimum cost for the design of reinforced-concrete strap combined footings under biaxial bending, with each column using a genetic algorithm.
Arnulfo Luévanos-Rojas, Griselda Santiago-Hurtado, Victor Manuel Moreno-Landeros, Francisco Javier Olguin-Coca, Luis Daimir López-León, Eyran Roberto Diaz-Gurrola   +5 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source