Results 241 to 250 of about 2,175,232 (349)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Freezing and unfreezing of antiferromagnetic spins in CoO(111) epitaxial films on a ferromagnetic support. [PDF]

Sci Rep
Kwiatkowski A, Szpytma M, Świerkosz E, Oleś E, Dróżdż P, Kozioł-Rachwał A, Zając M, Partyka-Jankowska E, Ślęzak T, Ślęzak M.   +9 more
europepmc   +1 more source

Spiritual Moments [PDF]

The Permanente Journal, 2005
openaire   +2 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

The Effects of Visual and Audio Secondary Cognitive Tasks During Landing: A Statistical Parametric Mapping Analysis of Hip and Knee Biomechanics. [PDF]

Int J Exerc Sci
Nguyen H, Lyle A, Tran K, Espinoza D, Hughes G.   +4 more
europepmc   +1 more source

A Theoretical Study on CH Bond Moment. ( II ) Determination of CH Bond Moments in Methane, Ethylene, and Acethlene from the Intensities of Bending Vibrations

, 1962
Shiro Maeda
openalex   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Daily Micro Moments (DMMs): A Feasibility Framework for Integrating Lifestyle Medicine to Enhance Physician Well-Being and Reduce Burnout. [PDF]

Cureus
Bukhari S.
europepmc   +1 more source