Results 41 to 50 of about 6,076 (222)
Nasal Drug Delivery Systems: An Overview [PDF]
, 2015 Since ancient times, drugs have been administered via the nasal route for therapeutic and recreational purposes. The interest in, and importance, of the systemic effects of drugs administered through the nasal route, have expanded over recent decades ...
Conway, Barbara R. +3 more
core +1 more source
Comparison of montelukast and mometasone furoate in the prevention of recurrent nasal polyps
Therapeutic Advances in Respiratory Disease, 2012 Background: The aim of our study was to compare the effects of montelukast and mometasone furoate nasal spray on the postoperative course of patients with nasal polyposis.
Erkan Vuralkan +6 more
doaj +1 more source
Olfactory Bulb Volume and Function Recovery in Eosinophilic Chronic Rhinosinusitis
The Laryngoscope, EarlyView.This study investigated perioperative changes in olfactory bulb volume (OBV) in patients with eosinophilic chronic rhinosinusitis using high‐resolution 3T MRI. Postoperative increases in OBV were associated with improvements in olfactory identification, suggesting a potential link between olfactory bulb structural plasticity and functional recovery ...
Keisuke Yamamoto +8 more
wiley +1 more source
Glucocorticoids for human skin: New aspects of the mechanism of action [PDF]
, 2005 Topical glucocorticoids have always been considered first-line drugs for inflammatory diseases of the skin and bronchial system. Applied systemically, glucocorticoids are used for severe inflammatory and immunological diseases and the inhibition of ...
Ahmed, M. +4 more
core +1 more source
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Background Chronic rhinosinusitis (CRS) and nasal polyps (NP) are chronic inflammatory conditions with unsatisfactory treatment outcomes due to frequent recurrence of refractory disease. Identifying new therapeutic targets is essential. Methods We conducted a proteome‐wide Mendelian randomization (MR) analysis by integrating genome‐wide ...
En Zhou +4 more
wiley +1 more source
Use of Mometasone furoate in prolonged treatment of experimental spinal cord injury in mice: A comparative study of three different glucocorticoids [PDF]
, 2015 Traumatic spinal cord injury (SCI) represents one of the most disabling injuries of the human body causing temporary or permanent sensory and/or motor system deficit, particularly hind limb locomotor function impairment.
Bramanti, Placido +6 more
core +1 more source
Allergy, EarlyView.The RHAPSODY multinational study investigated 26 months of continuous treatment with 5‐grass‐pollen sublingual SLIT drops in adults with moderate‐to‐severe grass‐pollen‐induced allergic rhinoconjunctivitis. The primary efficacy endpoint (the average daily total combined score) showed statistically significant differences in favour of the active ...
Alain Didier +4 more
wiley +1 more source
EFFICACY AND SAFETY OF USING MOMETASONE FUROATE IN CHILDREN WITH ATOPIC DERMATITIS
Педиатрическая фармакология, 2009 The article describes the therapy for atopic dermatitis with topical glucocorticosteroids. Parameters of the «ideal» topical cortico steroid are provided: strong anti-inflammatory effect, low systemic bioavailability, quick action onset, minimal side ...
A.Yu. Tomilova +3 more
doaj +2 more sources
A Novel Approach to Assess the Potency of Topical Corticosteroids
Pharmaceutics, 2021 The potencies of topical corticosteroid products have mainly been classified using clinical data but in some instances, the US Food and Drug Administration’s (FDA’s) vasoconstrictor assay (VCA) to assess the skin blanching response has also been used ...
Michael Zvidzayi +4 more
doaj +1 more source
Allergy, EarlyView.ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter +20 more
wiley +1 more source