Early Denosumab for the prevention of osteoporotic fractures in breast cancer women undergoing aromatase inhibitors: A case-control retrospective study [PDF]
BACKGROUND:Aromatase inhibitors (AIs) might have a detrimental impact on bone health in breast cancer (BC) women.Denosumab has been shown to reduce the risk of fractures, but the appropriate time for starting is yet to be clearly defined.OBJECTIVE:To ...
Cuntrera Daniele+8 more
core +1 more source
Common human diseases prediction using machine learning based on survey data [PDF]
In this era, the moment has arrived to move away from disease as the primary emphasis of medical treatment. Although impressive, the multiple techniques that have been developed to detect the diseases. In this time, there are some types of diseases COVID-19, normal flue, migraine, lung disease, heart disease, kidney disease, diabetics, stomach disease,
arxiv
The ‘Vanishing Breast’: An Unusual Presentation of Infiltrating Ductal Carcinoma [PDF]
Introduction: Breast cancer is a leading cause of cancer related morbidity and mortality world over. Most cases will present as palpable lump or bloody nipple discharge. However, there are cases of atypical presentation in the literature.Case summary: We
Ilkul, JH, Mwenda, AS
core +2 more sources
Lymphangiogenesis in breast carcinoma is present but insufficient for metastatic spread [PDF]
Introduction: The lymphatic vasculature is an important route for the metastatic spread of human cancer. However, the extent to which this depends on lymphangiogenesis or on invasion of existing lymph vessels remains controversial. The goal of this study
Babić, Mirsad+5 more
core +3 more sources
The role of mutation rate variation and genetic diversity in the architecture of human disease [PDF]
We have investigated the role that the mutation rate and the structure of genetic variation at a locus play in determining whether a gene is involved in disease. We predict that the mutation rate and its genetic diversity should be higher in genes associated with disease, unless all genes that could cause disease have already been identified ...
arxiv +1 more source
Unveiling new disease, pathway, and gene associations via multi-scale neural networks [PDF]
Diseases involve complex processes and modifications to the cellular machinery. The gene expression profile of the affected cells contains characteristic patterns linked to a disease. Hence, biological knowledge pertaining to a disease can be derived from a patient cell's profile, improving our diagnosis ability, as well as our grasp of disease risks ...
arxiv +1 more source
A Mondor’s disease is a rare, benign and self-limiting condition. It is due to thrombophlebitis of the superficial veins of the breast and chest wall. It usually occurs in middle-aged women who present with a palpable cordlike structure, often painful ...
Che Mohamed, Siti Kamariah+1 more
core
In‐hospital and 1 year incremental prognostic value of drug abuse detection in acute heart failure
Abstract Aims The study aims to assess the in‐hospital and 1 year incremental prognostic value of recent drug abuse use, detected by a systematic urinary screening, in a consecutive cohort of patients hospitalized for acute heart failure (AHF). Methods All patients admitted for AHF with a drug abuse screening using a urinary assay were included in this
Charles Fauvel+110 more
wiley +1 more source
Surgical management of penile mondor’s disease: Case report and brief review of literature [PDF]
Penile Mondor’s disease (PMD) is a rare condition characterized by thrombosis of superficial dorsal vein of the penis. PMD is usuallycaused due to vigorous sex or repeated trauma to the penis leading to painful swelling of the penis. Most of the patients
Gahlawat, Sumit+3 more
core +2 more sources
Abstract Aims Despite the high risk of rehospitalization for heart failure (HF) and death among patients admitted to the intensive cardiac care unit (ICCU), no accurate prediction score for these outcomes exists. We aimed to develop a risk score to predict unplanned HF hospitalization and death 1‐year post‐discharge in an unselected cohort of patients ...
Andreas Bugge Tinggaard+116 more
wiley +1 more source