DomainScope: A disease network based on protein domain connections [PDF]
Protein domains are highly conserved functional units of proteins. Because they carry functionally significant information, the majority of the coding disease variants are located on domains. Additionally, domains are specific units of the proteins that can be targeted for drug delivery purposes.
arxiv
The PNH French Working Group Experience: Building a Strong Network of Cytometrists
ABSTRACT Introduction The PNH working group was created in 2010 to initiate a workshop on testing white blood cells to share international recommendations. Methods Thirty‐five French and Belgian laboratories equipped with 2‐ or 3‐laser cytometers applied three different panels with or without FLAER reagent in 305 samples.
Orianne Wagner‐Ballon+9 more
wiley +1 more source
The impact of high-intensity interval training exercise on breast cancer survivors: a pilot study to explore fitness, cardiac regulation and biomarkers of the stress systems [PDF]
Background Cardiovascular disease (CVD) remains the largest cause of death in breast cancer survivors. The aim of this study was to explore the impact of exercise intensity on aerobic fitness and autonomic cardiac regulation (heart rate variability (HRV)
Cooke, Julie+7 more
core +2 more sources
Correlation-based Discovery of Disease Patterns for Syndromic Surveillance [PDF]
Early outbreak detection is a key aspect in the containment of infectious diseases, as it enables the identification and isolation of infected individuals before the disease can spread to a larger population. Instead of detecting unexpected increases of infections by monitoring confirmed cases, syndromic surveillance aims at the detection of cases with
arxiv
International Journal of Medical Students - Year 2013 - Volume 1 - Supplement 2 [PDF]
International Journal of Medical Students - Year 2013 - Volume 1 - Supplement 2 Abstracts of the 18th Academic Medical Congress of ...
IJMS, Executive Committee of
core +2 more sources
A post hoc analysis of Severity of Alopecia Tool (SALT) score trajectories in patients with alopecia areata who received ritlecitinib 50 mg once‐daily in ALLEGRO‐2b/3 and rolled over into the ongoing, open‐label, Phase 3 ALLEGRO‐LT study. Long‐term response patterns up to Month 24 and variables associated with treatment response are described. Abstract
B. King+15 more
wiley +1 more source
Time series analysis of Parkinson's disease, Huntington's disease and Amyotrophic Lateral Sclerosis [PDF]
The aim of this paper is to study the (clinical) time-series data of three diseases with complex dynamics: Parkinson's disease, Huntington's disease and Amyotrophic Lateral Sclerosis. For this purpose, first all of the time series data are embedded in a vector space of suitable dimension and then the correlation dimension of the above mentioned ...
arxiv
Analysis of the human diseasome reveals phenotype modules across common, genetic, and infectious diseases [PDF]
Phenotypes are the observable characteristics of an organism arising from its response to the environment. Phenotypes associated with engineered and natural genetic variation are widely recorded using phenotype ontologies in model organisms, as are signs and symptoms of human Mendelian diseases in databases such as OMIM and Orphanet.
arxiv +1 more source
Environmental toxicity influences disease spread in consumer population [PDF]
The study of infectious disease has been of interest to ecologists since long. The initiation of epidemic and the long term disease dynamics are largely influenced by the nature of the underlying consumer (host)-resource dynamics. Ecological traits of such systems may be often modulated by toxins released in the environment due to ongoing anthropogenic
arxiv
Idiopathic Mondor's Disease of the Breast in an Outpatient Primary Care Center: A Case Report [PDF]
Introduction: Mondor's Disease (MD) is a thrombophlebitis of the anterolateral chest wall, with only about 400 cases reported worldwide, predominantly in women.
Castro-Goyes, Daniel Fernando+1 more
core +2 more sources